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Table 13 Univariable analysis regarding predictors for LGE presence

From: Identification of cardiomyopathy associated circulating miRNA biomarkers in patients with muscular dystrophy using a complementary cardiovascular magnetic resonance and plasma profiling approach

Variable (N = 63)

OR (95 % CI)

p value

Age, years

1.03 (0.99–1.08)

0.13

BMD, n (%)

4.16 (0.49–35.28)

0.19

Skeletal muscle status 0/1/2/3, n (%)

2.83 (0.84–9.50)

0.09

Log10 CK, U/L

1.69 (0.39–7.36)

0.48

LV-EDVi, ml/m2

1.02 (0.99–1.05)

0.06

LV-ESVi, ml/m2

1.11 (1.04–1.19)

0.003

LV-mass, g/m2

1.06 (1.01–1.11)

0.024

LV-EF, %

0.81 (0.71–0.91)

0.001

Elevated hs-Trop, n (%)a

9.1 (1.85–44.87)

0.007

miR-222 (/103)c,d

2.51 (1.01–6.21)

0.047

miR-378a-5p (/103)c,d

1.00 (0.99–1.01)

0.86

miR-26a (/103)c

12.86 (1.07–154.34)

0.044

  1. a > 14 pg/mL
  2. (b) – Each miRNA plasma level was normalized to miR-16 plasma levels and thereafter multiplied by 103 in order to increase readability
  3. (c) - Log10 transformed before introduced in the regression analysis
  4. Bold text indicates a significant p-value of <0.05