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Table 13 Univariable analysis regarding predictors for LGE presence

From: Identification of cardiomyopathy associated circulating miRNA biomarkers in patients with muscular dystrophy using a complementary cardiovascular magnetic resonance and plasma profiling approach

Variable (N = 63) OR (95 % CI) p value
Age, years 1.03 (0.99–1.08) 0.13
BMD, n (%) 4.16 (0.49–35.28) 0.19
Skeletal muscle status 0/1/2/3, n (%) 2.83 (0.84–9.50) 0.09
Log10 CK, U/L 1.69 (0.39–7.36) 0.48
LV-EDVi, ml/m2 1.02 (0.99–1.05) 0.06
LV-ESVi, ml/m2 1.11 (1.04–1.19) 0.003
LV-mass, g/m2 1.06 (1.01–1.11) 0.024
LV-EF, % 0.81 (0.71–0.91) 0.001
Elevated hs-Trop, n (%)a 9.1 (1.85–44.87) 0.007
miR-222 (/103)c,d 2.51 (1.01–6.21) 0.047
miR-378a-5p (/103)c,d 1.00 (0.99–1.01) 0.86
miR-26a (/103)c 12.86 (1.07–154.34) 0.044
  1. a > 14 pg/mL
  2. (b) – Each miRNA plasma level was normalized to miR-16 plasma levels and thereafter multiplied by 103 in order to increase readability
  3. (c) - Log10 transformed before introduced in the regression analysis
  4. Bold text indicates a significant p-value of <0.05