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Table 4 Patient characteristics and cardiac findings according to CMR results

From: Identification of cardiomyopathy associated circulating miRNA biomarkers in patients with muscular dystrophy using a complementary cardiovascular magnetic resonance and plasma profiling approach

 

MD

Normal CMR

Abnormal CMR

p value

N = 63

N = 14

N = 49

Male, n (%)

63 (100)

14 (100)

49 (100)

1.00

Age, years

31 ± 15

25 ± 18

32 ± 14

0.11

BMD, n (%)

51 (81)

13 (93)

38 (78)

0.27

BMI, kg/m2

24 ± 4

23 ± 6

24 ± 4

0.75

Skeletal muscle status 0/1/2/3, n (%)

2 (3)/43 (68)/13 (21)/5 (8)

2 (14)/10 (71)/1 (7)/1 (7)

33 (67)/12 (25)/4 (8)/0 (0)

0.07

ACE inhibitor, n (%)

16 (25)

1 (7)

15 (31)

0.09

Beta-blocker, n (%)

14 (22)

1 (7)

13 (27)

0.16

CK, U/L

1226 (653-2424)

764 (596-2411)

1344 (783-2463)

0.24

Elevated hs-Trop, n (%)a

30 (48)

2 (14)

28 (57)

0.006

Elevated NT-proBNP, n (%)b

3 (5)

0 (0)

3 (6)

1.00

  1. a > 14 pg/mL; b > 450 pg/mL
  2. Bold text indicates a significant p-value of <0.05