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Table 1 Serial blood cobalt and chromium levels with concurrent myocardial and hepatic T2*

From: Detection of metallic cobalt and chromium liver deposition following failed hip replacement using T2* and R2 magnetic resonance

  Scan Date (month/year) LVEF (%) EDV (ml) ESV (ml) Mass (g) Cardiac T2* (ms) (LLN 20 ms) Liver T2* (ms) (LLN 6.3 ms) Equivalent liver iron concentration using FerriScan R2 (mg/g/dry tissue) Blood Co (ULN 0.9mcg/L) Blood Cr (ULN <0.3mcg/L)
1 Apr-14 68 142 46 127 29 4.2 3.9 9976 393
2 Oct-14 66 139 47 122 24 3.3 5.6 392 200
3 Jan-15 60 143 58 129 36 3 5.3 276 192
4 Jun-15 65 145 51 113 27 2.9 5.3 151 132
  1. Myocardial T2* values were normal. Short hepatic T2* values (normal greater than 6.2 ms) indicate the presence of metal. Despite falling blood metal ion levels, liver MR results suggested increasing tissue deposition. Ferriscan measurements demonstrate the detectable signal change and iron equivalent for an iron-loaded patient. (LLN lower limit of normal, ULN upper limit of normal)