Fig. 2

a Example first-pass perfusion images obtained from a mouse at rest. These images show the arrival of contrast agent in the right ventricle (i), left ventricle (ii and iii) and the myocardium (iv). b Rest perfusion measurements in the control and HFD mice at 6, 12, 18 and 24 weeks post-diet. c Stress perfusion measurements in the control and HFD mice at 6, 12, 18 and 24 weeks post-diet (*p < 0.05 vs. age-matched control). d Myocardial perfusion reserve (MPR) measurements in the control and HFD mice (*p < 0.05 vs. age-matched control)