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Table 2 Parameters of cardiac and myocardial geometry and function

From: Early-stage heart failure with preserved ejection fraction in the pig: a cardiovascular magnetic resonance study

  Controls (n = 7) DOCA (n = 5) Controls vs. DOCA
Parameter Rest Stress p Rest Stress p prest pstress
LVMM (g · m−2) 84 ± 7    111 ± 9    <0.001  
WTED (mm · m−2) 6.3 ± 1.2 6.2 ± 1.4 0.934 8.3 ± 0.8 9.3 ± 1.6 0.224 0.007 0.006
WTES (mm · m−2) 9.6 ± 1.6 11.8 ± 2.2 0.009 13.0 ± 1.4 15.5 ± 1.9 0.012 0.003 0.012
WTH (mm · m−2) 3.3 ± 0.8 5.6 ± 1.7 0.019 4.8 ± 0.9 6.2 ± 1.1 0.074 0.020 0.489
MAPSE (mm) 11.1 ± 3.6 15.0 ± 3.7 0.078 6.9 ± 1.2 13.5 ± 4.9 0.040 0.037 0.586
EF (%) 52 ± 3 69 ± 7 0.001 53 ± 5 70 ± 2 < 0.001 0.840 0.749
EDV (ml · m−2) 124 ± 15 117 ± 12 0.293 125 ± 18 102 ± 26 0.008 0.862 0.203
ESV (ml · m−2) 59 ± 9 36 ± 10 0.005 59 ± 10 30 ± 9 < 0.001 0.983 0.360
SV (ml · m−2) 65 ± 8 81 ± 9 0.003 66 ± 11 71 ± 17 0.352 0.781 0.244
CI (l min−1 · m−2) 5.8 ± 0.9 9.4 ± 1.1 < 0.001 5.8 ± 1.0 7.8 ± 1.2 0.002 0.890 0.041
PER (ml · s−1 · m−2) −380 ± 54 −711 ± 219 0.005 −419 ± 95 −639 ± 114 0.002 0.389 0.523
PFRE (ml · s−1 · m−2) 307 ± 41 470 ± 75 0.002 332 ± 69 471 ± 49 0.007 0.449 0.979
PFRA (ml · s−1 · m−2) 302 ± 73 345 ± 99 0.223 334 ± 133 277 ± 118 0.192 0.599 0.304
LAVmax (ml · m−2) 34 ± 4 32 ± 8 0.444 48 ± 17 34 ± 14 0.012 0.042 0.798
LAVmin (ml · m−2) 14 ± 3 14 ± 4 0.655 25 ± 9 21 ± 8 0.222 0.012 0.054
LATEF (%) 58 ± 4 58 ± 11 0.990 48 ± 14 36 ± 10 0.265 0.104 0.006
  1. LVMM left ventricular muscle mass, WT ED end-diastolic wall thickness, WT ES end-systolic wall thickness, WTH wall thickening, MAPSE mitral annular plane systolic excursion, EF left ventricular ejection fraction, EDV left ventricular end-diastolic volume, ESV left ventricular end-systolic volume, SV left ventricular stroke volume, CI left ventricular cardiac index, PER peak ejection rate, PFR E early diastolic peak filling rate, PFR A late diastolic peak filling rate, LAV max left atrial maximum volume, LAV min left atrial minimal volume, LATEF left atrial total ejection fraction
  2. p is related to the rest-stress comparison within each group. prest and pstress relate to group comparisons at rest and stress, respectively