Skip to main content

Table 2 Parameters of cardiac and myocardial geometry and function

From: Early-stage heart failure with preserved ejection fraction in the pig: a cardiovascular magnetic resonance study

 

Controls (n = 7)

DOCA (n = 5)

Controls vs. DOCA

Parameter

Rest

Stress

p

Rest

Stress

p

prest

pstress

LVMM (g · m−2)

84 ± 7

  

111 ± 9

  

<0.001

 

WTED (mm · m−2)

6.3 ± 1.2

6.2 ± 1.4

0.934

8.3 ± 0.8

9.3 ± 1.6

0.224

0.007

0.006

WTES (mm · m−2)

9.6 ± 1.6

11.8 ± 2.2

0.009

13.0 ± 1.4

15.5 ± 1.9

0.012

0.003

0.012

WTH (mm · m−2)

3.3 ± 0.8

5.6 ± 1.7

0.019

4.8 ± 0.9

6.2 ± 1.1

0.074

0.020

0.489

MAPSE (mm)

11.1 ± 3.6

15.0 ± 3.7

0.078

6.9 ± 1.2

13.5 ± 4.9

0.040

0.037

0.586

EF (%)

52 ± 3

69 ± 7

0.001

53 ± 5

70 ± 2

< 0.001

0.840

0.749

EDV (ml · m−2)

124 ± 15

117 ± 12

0.293

125 ± 18

102 ± 26

0.008

0.862

0.203

ESV (ml · m−2)

59 ± 9

36 ± 10

0.005

59 ± 10

30 ± 9

< 0.001

0.983

0.360

SV (ml · m−2)

65 ± 8

81 ± 9

0.003

66 ± 11

71 ± 17

0.352

0.781

0.244

CI (l min−1 · m−2)

5.8 ± 0.9

9.4 ± 1.1

< 0.001

5.8 ± 1.0

7.8 ± 1.2

0.002

0.890

0.041

PER (ml · s−1 · m−2)

−380 ± 54

−711 ± 219

0.005

−419 ± 95

−639 ± 114

0.002

0.389

0.523

PFRE (ml · s−1 · m−2)

307 ± 41

470 ± 75

0.002

332 ± 69

471 ± 49

0.007

0.449

0.979

PFRA (ml · s−1 · m−2)

302 ± 73

345 ± 99

0.223

334 ± 133

277 ± 118

0.192

0.599

0.304

LAVmax (ml · m−2)

34 ± 4

32 ± 8

0.444

48 ± 17

34 ± 14

0.012

0.042

0.798

LAVmin (ml · m−2)

14 ± 3

14 ± 4

0.655

25 ± 9

21 ± 8

0.222

0.012

0.054

LATEF (%)

58 ± 4

58 ± 11

0.990

48 ± 14

36 ± 10

0.265

0.104

0.006

  1. LVMM left ventricular muscle mass, WT ED end-diastolic wall thickness, WT ES end-systolic wall thickness, WTH wall thickening, MAPSE mitral annular plane systolic excursion, EF left ventricular ejection fraction, EDV left ventricular end-diastolic volume, ESV left ventricular end-systolic volume, SV left ventricular stroke volume, CI left ventricular cardiac index, PER peak ejection rate, PFR E early diastolic peak filling rate, PFR A late diastolic peak filling rate, LAV max left atrial maximum volume, LAV min left atrial minimal volume, LATEF left atrial total ejection fraction
  2. p is related to the rest-stress comparison within each group. prest and pstress relate to group comparisons at rest and stress, respectively