Skip to main content

Table 6 Lateral values of native T1 and ECV within subgroups of the DMD cohort

From: Native T1 values identify myocardial changes and stratify disease severity in patients with Duchenne muscular dystrophy

Technique

Location

Measurement

Age < 14

 

Age > 14

  

Average

SD

Average

SD

p

MOLLI

Lateral

Native T1

1070.3

52.7

1078.4

82.3

0.56

  

ECVa

29.6

5.5

32.4

7.1

0.03

SASHA

Lateral

Native T1

1279.7

76

1260.8

78.7

0.25

  

ECVa

25.6

4.1

28.9

7.4

0.01

   

LVEF b  > 55 %

 

LVEF b  < 55 %

  

Average

SD

Average

SD

p

MOLLI

Lateral

Native T1

1061.4

52.2

1096.6

90.8

0.04

  

ECVa

29.3

5.0

34.4

7.7

<0.01

SASHA

Lateral

Native T1

1263.8

72.2

1276.4

86.5

0.47

  

ECVa

24.9

4.1

31.7

7.3

<0.01

   

LGE c -

 

LGE c +

  

Average

SD

Average

SD

p

MOLLI

Lateral

Native T1

1046.5

48.0

1094.8

78.6

<0.01

  

ECVa

27.7

3.9

33.7

7.1

<0.01

SASHA

Lateral

Native T1

1255.4

75.8

1277.8

78.5

0.16

  

ECVa

23.5

3.4

30.3

6.6

<0.01

  1. Lateral values of native T1 and ECV using the MOLLI and SASHA techniques for measuring T1 within subgroups of the DMD cohort divided into those < 14 years (n = 12), and those > 14 years (n = 8); divided again into those with LVEF > 55 % (n = 12) and LVEF < 55 % (n = 8); divided again into those with LGE (n = 8) and those without LGE (n = 12). In this case, using regions of interest that would contain LGE if present, significant differences are found in ECV measurements across the board, and in Native T1 measurements using MOLLI. a ECV extracellular volume fraction, bLVEF left ventricular ejection fraction, cLGE late gadolinium enhancement