Objective criteria for septal fibrosis in non-ischemic dilated cardiomyopathy: validation for the prediction of future cardiovascular events

Table 2 CMR Characteristics of the Cohort and Stratified by Primary Outcome Measure

Characteristics	Total cohort (N = 118)	With primary outcome (N = 20)	Without primary outcome (N = 98)	P-value
LVEDVI (ml/m²)	119 ± 42	128 ± 32	117 ± 43	0.12
LVESVI (ml/m²)	84 ± 40	97 ± 33	82 ± 41	0.06
LVEF (%)	32 ± 12	26 ± 11	33 ± 12	0.02*
LV mass index (g/m²)	95 ± 29	92 ± 28	96 ± 30	0.58
RVEDVI (ml/m²)	69 ± 23	77 ± 20	68 ± 24	0.09
RVESVI (ml/m²)	40 ± 22	47 ± 19	38 ± 23	0.02*
RVEF (%)	45 ± 17	40 ± 16	46 ± 17	0.10
LGE – Qualitative (Visual)
Any LGE, n (%)	66 (56)	16 (80)	50 (51)	0.03*
Septal LGE, n (%)	37 (31)	11 (55)	26 (27)	0.02*
RV insertion site LGE, n (%)	38 (32)	10 (50)	28 (29)	0.07
Septal and/or RV insertion site LGE, n (%)	55 (47)	15 (75)	40 (41)	<0.01*
LGE – Quantitative
Total LGE -5SD (%)	5.6 ± 9.0	7.4 ± 9.4	5.2 ± 8.9	0.22
Total LGE -3SD (%)	14.3 ± 14.2	18.8 ± 15.1	13.3 ± 13.9	0.11
Total LGE -2SD (%)	24.5 ± 16.8	31.1 ± 17.8	23.1 ± 16.4	0.05
Septal LGE -5SD (%)	2.9 ± 3.6	5.4 ± 5.0	2.4 ± 3.0	<0.01*
Septal LGE -3SD (%)	6.9 ± 6.3	11.7 ± 8.5	5.9 ± 5.2	<0.01*
Septal LGE -2SD (%)	11.1 ± 7.5	16.9 ± 9.5	9.9 ± 6.5	<0.01*

Continuous data are expressed as mean ± SD, categorical data as n (%). *p < 0.05
Abbreviations: LV Left ventricular, EDVI End diastolic volume indexed to body surface area, ESVI End systolic volume indexed to body surface area, EF Ejection fraction, RV Right ventricular, LGE Late gadolinium enhancement
LGE was quantified by signal threshold versus reference mean (STRM) technique using signal intensity threshold of 5SD, 3SD and 2SD of the remote myocardium. Total LGE and septal LGE burden were expressed as percentage of the LV mass (%)

ISSN: 1532-429X