Fig. 3

Schematic representation of the influence of the decrease in systemic vascular resistance in the mechanisms leading to reverse remodeling (where stroke volume (SV) may be improved owing to an increase in ejection fraction (EF) with a decrease in end-systolic volume (ESV)) but not to adverse remodeling (where SV improvement is attributable to an increase in end-diastolic volume (EDV) in link with MI severity and especially of microvascular obstruction). Note that adverse and reverse remodeling correspond to different mechanisms and may thus coexist in the same patients