Baseline | 6 months | p-value | |
---|---|---|---|
Main medications | |||
- Beta-blockers | 100 (83%) | 101 (84%) | |
- ACE inhibitors | 103 (85%) | 104 (86%) | |
- Statins | 110 (91%) | 105 (87%) | |
- Antiplatelet therapy | 120 (99%) | 115 (95%) | |
Body mass index (kg.m−2) | 25 ± 4 | 25 ± 4 | |
Heart rate (bpm) | 66 ± 11 | 57 ± 8 | < 0.001 |
BP parameters | |||
Systolic BP (mmHg) | 129 ± 21 | 130 ± 20 | |
Diastolic BP (mmHg) | 75 ± 14 | 72 ± 11 | |
Mean BP (mmHg) | 93 ± 15 | 92 ± 13 | |
Cardiac parameters | |||
LV end-diastolic volume (mL.m−2) | 92 ± 15 | 96 ± 18 | 0.006 |
LV ejection fraction (%) | 42 ± 8 | 49 ± 9 | < 0.001 |
Total MI area (% of LV) | 22 ± 12 | 16 ± 11 | < 0.001 |
Transmural MI - presence (%) | 94 (78%) | 55 (46%) | < 0.001 |
- area (% of LV) | 16 ± 13 | 8 ± 11 | < 0.001 |
MVO - presence (%) | 59 (49%) | 0 (0%) | < 0.001 |
- area (% of LV) | 8 ± 11 | 0 ± 0 | < 0.001 |
SV-derived parameters | |||
SV (mL.m−2) | 38 ± 8 | 47 ± 9 | < 0.001 |
Cardiac index (L.min−1.m−2) | 2.4 ± 0.4 | 2.6 ± 0.5 | < 0.001 |
TPVR (mmHg.min.m2.L−1) | 39 ± 11 | 36 ± 9 | 0.001 |
TAC (mL.m−2.mmHg−1) | 0.74 ± 0.21 | 0.83 ± 0.22 | < 0.001 |
Ea (mmHg.m2.mL−1) | 2.6 ± 0.9 | 2.1 ± 0.6 | < 0.001 |
Stroke Work (L.mmHg.m−2) | 3.5 ± 0.9 | 4.3 ± 1.0 | < 0.001 |