Table 1 Characteristics of study subjects: healthy controls and patients (n = 212)
1.5 T Controls n = 29 | 1.5 T Patients n = 75 | 3 T Controls n = 22 | 3 T Patients n = 86 | |
|---|---|---|---|---|
Age (years) | 54 ± 17 | 65 ± 9* | 43 ± 12 | 60 ± 14* |
Men (%) | 21 (72) | 58 (77) | 13 (59) | 58 (67) |
Body mass index (kg/m2) | 25 ± 4 | 28 ± 5 | 26 ± 3 | 28 ± 4 |
Hematocrit | 0.42 ± 0.03 | 0.43 ± 0.03 | 0.42 ± 0.04 | 0.42 ± 0.03 |
CMR hemodynamic data | ||||
Rest HR (bpm) | 66 ± 11 | 62 ± 15 | 62 ± 12 | 65 ± 10 |
Stress HR (bpm) | 96 ± 15 | 79 ± 15* | 95 ± 12 | 91 ± 14 |
Rest SBP (mmHg) | 133 ± 21 | 139 ± 19 | 127 ± 14 | 136 ± 19 |
Stress SBP (mmHg) | 127 ± 19 | 133 ± 19 | 122 ± 16 | 126 ± 19 |
Rest RPP (bpm.mmHg) | 8800 ± 2200 | 8600 ± 2200 | 7600 ± 1700 | 8700 ± 2000 |
Stress RPP (bpm.mmHg) | 12,200 ± 2600 | 10,500 ± 2500* | 12,000 ± 2200 | 11,700 ± 2700 |
Adenosine symptoms | 29 (100) | 75 (100) | 22 (100) | 86 (100) |
Co-morbidities | ||||
Current smoker | 3 (10) | 2 (3) | 2 (9) | 12 (14) |
Ex-smoker | 3 (10) | 21 (28) | 3 (14) | 21 (24) |
Hypertension | - | 28 (37) | - | 24 (28) |
Hyperlipidemia | - | 23 (31) | - | 23 (27) |
Stroke/TIA | - | 2 (3) | - | 2 (2) |
Medications | ||||
Aspirin | - | 36 (48) | - | 35 (41) |
Beta-blocker | - | 34 (45)# | - | 19 (22) |
ACEi/ARB | - | 36 (48) | - | 39 (45) |
Statin | - | 31 (41)# | - | 44 (51) |
Nitrates | - | 3 (4) | 4 (5) | |
CCB (non-DHP) | - | 13 (17)# | - | 0 (0) |
CCB (DHP) | 4 (5) | 7 (8) |