Table 11 Exclusion criteria
| Â | Number (%) |
|---|---|
Age | |
  > 74 years | 119 (2%) |
Medical conditions | |
 Hypertension | 1382 (28%) |
 High cholesterol | 787 (16%) |
 Asthma | 628 (13%) |
 Hypothyroidism/myxoedema | 322 (6%) |
 Diabetes | 204 (4%) |
 Essential hypertension | 130 (3%) |
 Angina | 127 (3%) |
 Heart attack/myocardial infarction | 104 (2%) |
 Deep venous thrombosis (DVT) | 87 (2%) |
 Type 2 diabetes | 83 (2%) |
 Atrial fibrillation | 65 (1%) |
 Rheumatoid arthritis | 58 (1%) |
 Stroke | 58 (1%) |
 Emphysema/chronic bronchitis | 56 (1%) |
 Hyperthyroidism/thyrotoxicosis | 44 (1%) |
 Heart valve problem/heart murmur | 42 (1%) |
 Transient ischaemic attack (TIA) | 39 (1%) |
 Chronic obstructive airways disease/COPD | 39 (1%) |
 Pulmonary embolism +/− DVT | 38 (1%) |
 Iron deficiency anaemia | 33 (1%) |
 Ulcerative colitis | 31 (1%) |
 Heart arrhythmia | 31 (1%) |
 Heart/cardiac problem | 31 (1%) |
 Sleep apnoea | 28 (1%) |
 Polymyalgia rheumatica | 28 (1%) |
 Miscarriage | 22 (0%) |
 Irregular heart beat | 21 (0%) |
 Gestational hypertension/pre-eclampsia | 20 (0%) |
 Doctor diagnosed bronchiectasis_Yes | 18 (0%) |
 Anaemia | 18 (0%) |
 Ankylosing spondylitis | 18 (0%) |
 Rheumatic fever | 16 (0%) |
 Sarcoidosis | 15 (0%) |
 Peripheral vascular disease | 14 (0%) |
 Bronchiectasis | 14 (0%) |
 Diabetic eye disease | 14 (0%) |
 Crohns disease | 13 (0%) |
 Pernicious anaemia | 11 (0%) |
 Gestational diabetes only_Yes | 9 (0%) |
 Clotting disorder/excessive bleeding | 9 (0%) |
 SVT / supraventricular tachycardia | 9 (0%) |
 Other respiratory problems | 8 (0%) |
 Sjogren’s syndrome/sicca syndrome | 8 (0%) |
 Systemic lupus erythematosis/SLE | 8 (0%) |
 Renal/kidney failure | 8 (0%) |
 Low platelets/platelet disorder | 7 (0%) |
 Type 1 diabetes | 7 (0%) |
 Grave’s disease | 6 (0%) |
 Heart failure/pulmonary edema | 6 (0%) |
 Gestational diabetes | 5 (0%) |
 Hereditary/genetic haematological disorder | 5 (0%) |
 Cardiomyopathy | 5 (0%) |
 Hyperparathyroidism | 5 (0%) |
 Nephritis | 5 (0%) |
 Haemochromatosis | 5 (0%) |
 Connective tissue disorder | 4 (0%) |
 Renal failure not requiring dialysis | 4 (0%) |
 Polycythaemia vera | 4 (0%) |
 Neutropenia/lymphopenia | 4 (0%) |
 Anorexia/bulimia/other eating disorder | 4 (0%) |
 Surgery/amputation of toe or leg_Do not know | 4 (0%) |
 Lymphoedema | 4 (0%) |
 Aortic stenosis | 4 (0%) |
 Retinal artery/vein occlusion | 4 (0%) |
 Inflammatory bowel disease | 3 (0%) |
 Adrenocortical insufficiency/Addison’s disease | 3 (0%) |
 Hyperprolactinaemia | 3 (0%) |
 Surgery/amputation of toe or leg_Yes, toes | 3 (0%) |
 Atrial flutter | 3 (0%) |
 Mitral regurgitation/incompetence | 3 (0%) |
 Pericarditis | 3 (0%) |
 Hypertrophic cardiomyopathy (HCM / HOCM) | 3 (0%) |
 Emphysema | 3 (0%) |
 Kidney nephropathy | 3 (0%) |
 Myocarditis | 2 (0%) |
 Liver failure/cirrhosis | 2 (0%) |
 Diabetic neuropathy/ulcers | 2 (0%) |
 Leg claudication/intermittent claudication | 2 (0%) |
 Mitral valve disease | 2 (0%) |
 Mitral valve prolapse | 2 (0%) |
 Monoclonal gammopathy/not myeloma | 2 (0%) |
 Glomerulnephritis | 1 (0%) |
 Haemophilia | 1 (0%) |
 Vasculitis | 1 (0%) |
 Wegners granulmatosis | 1 (0%) |
 Sickle cell disease | 1 (0%) |
 Microscopic polyarteritis | 1 (0%) |
 Myositis/myopathy | 1 (0%) |
 Pericardial problem | 1 (0%) |
 Pleural plaques (not known asbestosis) | 1 (0%) |
 Hyperaldosteronism/Conn’s syndrome | 1 (0%) |
 Polymyositis | 1 (0%) |
 Hypopituitarism | 1 (0%) |
 Interstitial lung disease | 1 (0%) |
 Alcoholic liver disease/alcoholic cirrhosis | 1 (0%) |
 Antiphospholipid syndrome | 1 (0%) |
 Aortic aneurysm | 1 (0%) |
 Aortic regurgitation/incompetence | 1 (0%) |
 Aplastic anaemia | 1 (0%) |
 Diabetes insipidus | 1 (0%) |
 Fibrosing alveolitis/unspecified alveolitis | 1 (0%) |
 Giant cell/temporal arteritis | 1 (0%) |
 Iga nephropathy | 1 (0%) |
 Myeloproliferative disorder | 1 (0%) |
 Pericardial effusion | 1 (0%) |
 Pleural effusion | 1 (0%) |
 Respiratory failure | 1 (0%) |
 Sick sinus syndrome | 1 (0%) |
 Wolff parkinson white/WPW syndrome | 1 (0%) |
 Surgery/amputation of toe or leg_Yes, leg above the knee | 1 (0%) |
 Surgery/amputation of toe or leg_Yes, leg below the knee | 1 (0%) |
Medications | |
 Cholesterol lowering medication | 784 (16%) |
 Blood pressure medication | 705 (14%) |
 Hormone replacement therapy | 331 (7%) |
 Insulin | 15 (0%) |
Symptoms | |
 Chest pain due to walking ceases when standing still_Yes | 264 (5%) |
 Chest pain or discomfort when walking uphill or hurrying_Yes | 229 (5%) |
 Chest pain or discomfort when walking uphill or hurrying_Unable to walk up hills or to hurry | 20 (0%) |
 Chest pain due to walking ceases when standing still_Do not know | 17 (0%) |
 Chest pain or discomfort when walking uphill or hurrying_Prefer not to answer | 2 (0%) |
 Shortness of breath walking on level ground_Yes | 386 (8%) |
 Shortness of breath walking on level ground_Do not know | 76 (2%) |
 Shortness of breath walking on level ground_Prefer not to answer | 5 (0%) |
Smoking history | |
 Ex-smoker | 1896 (38%) |
 Current smoker | 355 (7%) |
High body mass index | |
 BMI ≥ 30 | 1158 (23%) |
Ethnicity | |
 Other ethnic group | 30 (1%) |
 Indian | 29 (1%) |
 Pakistani | 19 (0%) |
 Caribbean | 19 (0%) |
 Chinese | 17 (0%) |
 Prefer not to answer | 17 (0%) |
 African | 16 (0%) |
 Any other mixed background | 15 (0%) |
 Any other Asian background | 12 (0%) |
 White and Black Caribbean | 8 (0%) |
 White and Asian | 7 (0%) |
 White and Black African | 5 (0%) |
 Bangladeshi | 2 (0%) |
 Do not know | 2 (0%) |
 Any other Black background | 1 (0%) |
 Asian or Asian British | 1 (0%) |