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Table 4 Cox proportional hazard analysis for prediction of all-cause death following valve intervention

From: Cardiovascular magnetic resonance evaluation of symptomatic severe aortic stenosis: association of circumferential myocardial strain and mortality

Variable

Univariate analysis

Multivariate analyisis

 

Hazard ratio (95% CI)

p-Value

Hazard ratio (95% CI)

p-Value

Age (per year)

1.125 (1.043–1.215)

0.002

1.084 (0.935–1.256)

0.286

STS score (per %)

1.238 (1.037–1.477)

0.018

1.365 (0.943–1.976)

0.099

eGFR (per ml/min/1.73 m2)

0.963 (0.936–0.991)

0.010

0.988 (0.947–1.053)

0.953

Baseline Mid LV CS (per %)

1.016 (1.007–1.024)

0.001

1.029 (1.007–1.052)

0.009

Baseline LVEF (per %)

0.962 (0.926–0.999)

0.046

1.031 (0.949–1.119)

0.473

TAVI procedure

3.776 (1.283–11.109)

0.016

0.397 (0.043–3.646)

0.414

Myocardial Fibrosis (LGE + ve)

1.670 (0.615–4.541)

0.315

-

-

Baseline LVMI

1.014 (0.993–1.035)

0.189

-

-

History of MI

0.611 (0.148–2.516)

0.495

-

-

Mean Aortic PG

1.018 (0.91–1.046)

0.182

-

-

Indexed LA volume

1.012 (0.982–1.043)

0.428

-

-

LV mass:volume ratio

8.051 (0.332–195.380)

0.200

-

-

Zva

1.788 (0.847–3.778)

0.128

-

-

BMI

1.211 (0.990–1.482)

0.062

-

-

Diabetes Mellitus

1.119 (0.162–7.744)

0.909

-

-

Hyperlipidaemia

1.795 (0.396–8.138)

0.448

-

-

Hypertension

0.578 (0.112–2.994)

0.514

-

-

Previous MI

0.960 (0.136–6.778)

0.967

-

-

Previous PCI

0.733 (0.101–5.305)

0.758

-

-

Previous CABG

0.243 (0.043–1.385)

0.111

-

-

Atrial Fibrillation

0.980 (0.144–6.673)

0.984

-

-

Stroke/TIA

0.742 (0.069–7.960)

0.805

-

-

Peripheral Vascular Disease

1.589 (0.145–17.400)

0.705

-

-

COPD

0.907 (0.125–6.586)

0.924

-

-

Pulmonary Hypertension

0.692 (0.112–4.267)

0.692

-

-