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Table 5 Inter-study variability in the patient group

From: Cardiovascular magnetic resonance myocardial feature tracking using a non-rigid, elastic image registration algorithm: assessment of variability in a real-life clinical setting

Inter-study # Bias LOA CV CR ICC (95% CI)
Expert Global ErrSAX 86 −2.25* [−13.7;9.2] 23.7 ±16.2 0.91 (0.85–0.95)
EccSAX 86 −0.31 [−7.0;6.3] 27.1 ±9.3 0.83 (0.75–0.89)
EllLAX 18 0.04 [−2.9;3.0]£ 12.3 ±4.2 0.95 (0.87–0.98)
Segm. ErrSAX 470 −2.33* [−21.7;17.0] 39.5 ±27.3 0.86 (0.83–0.89)
EccSAX 470 −0.16 [−10.7;10.3]£ 40.7 ±14.8 0.80 (0.76–0.83)
EllLAX 126 −0.14 [−10.5;10.2] 41.7 ±14.6 0.79 (0.71–0.85)
Skilled Observer Global ErrSAX 86 −2.36* [−13.1;8.4] 22.5 ±15.2 0.92 (0.86–0.95)
EccSAX 86 −0.12 [−6.4;6.2] 24.9 ±8.9 0.88 (0.82–0.92)
EllLAX 18 −0.16* [−3.1;2.8] 11.7 ±4.2 0.94 (0.86–0.98)
Segm. ErrSAX 470 −2.53* [−19.8;14.7]$ 35.6 ±24.4 0.88 (0.85–0.91)
EccSAX 470 0.01 [−6.9;8.5] 33.4 ±12.0 0.86 (0.83–0.88)
EllLAX 126 −0.18 [−12.9;12.5]$ 48.7 ±17.9 0.66 (0.54–0.74)
Beginner Global ErrSAX 86 −2.41* [−14.0;9.2] 24.1 ±16.4 0.91 (0.84–0.94)
EccSAX 86 −0.69 [−6.1;6.6] 26.3 ±10.3 0.84 (0.76–0.89)
EllLAX 18 −0.49 [−4.4;3.4]£ 15.8 ±5.5 0.90 (0.74–0.96)
Segm. ErrSAX 470 −2.47* [−23.1;18.1]£ 37.4 ±29.1 0.86 (0.83–0.88)
EccSAX 470 −0.65 [−12.0;10.7]£ 43.0 ±16.0 0.71 (0.67–0.74)
EllLAX 126 −0.35 [−12.4;11.7]£ 48.2 ±17.0 0.77 (0.65–0.85)
  1. # - Sample Size, LOA Limits of agreement; CV Coefficient of variation (#); CR Coefficient of repeatability; ICC Intraclass correlation coefficient
  2. *p < 0.05, two tailed paired t-test against zero
  3. $ p < 0.05, two tailed F-test between Expert versus Skilled observer variability
  4. £ p < 0.05, two tailed F-test between Expert versus Beginner variability