Skip to main content

Table 3 Regression model to identify association between segmental strain, segement thickness and tissue characteristics

From: Effect of cellular and extracellular pathology assessed by T1 mapping on regional contractile function in hypertrophic cardiomyopathy

  Segment thickness BIC LGE BIC Native T1 BIC Extracellular volume BIC
Ecc-FT Univariable Beta 1.325 (1.200;1.450) 5345.6 9.234 (7.444;11.024) 5592.9 0.039 (0.031;0.047) 5476.3 0.268 (0.168;0.368) 5368.1
P value <0.001   <0.001   <0.001   <0.001  
Multivariable 1 Beta 1.317 (1.165;1.470) 5074.1 1.294 (-0.601;3.191)     −0.046 (-0.136;0.045)  
P value <0.001   0.195     0.394  
  Multivariable 2 Beta 1.219 (1.070;1.368) 5214.3 0.331 (-1.470;2.131)   0.015 (0.008;0.022)    
P value <0.001   0.718   <0.001    
Err-FT Univariable Beta −3.573 (−3.963;−3.183) 7167.8 −25.595 (-30.940;-20.251) 7354.3 −0.118 (−0.142;−0.093) 7177.7 −0.693 (−0.991;−0.394) 6997.0
P value <0.001   <0.001   <0.001   <0.001  
Multivariable 1 Beta −3.532 (-4.011;-3.073) 6758.4 −4.861 (-10.661;0.941)     0.201 (-0.080;0.481)  
P value <0.001   0.101     0.161  
  Multivariable 2 Beta −3.193 (-3.659;-2.726) 6986.5 −1.266 (-6.868;4.336)   −0.053 (-0.075;-0.030)    
P value <0.001   0.658   <0.001    
Ecc-SPAMM Univariable Beta 1.039 (0.881;1.198) 3651.4 8.525 (6.382;10.667) 3738.8 0.033 (0.024;0.042) 3681.3 0.292 (0.167;0.417) 3601.5
P value <0.001   <0.001   <0.001   <0.001  
Multivariable 1 Beta 0.964 (0.782;1.146) 3451.0 2.603 (0.341;4.866)     0.061 (-0.055;0.177)  
P value <0.001   0.024     0.303  
  Multivariable 2 Beta 0.0849 (0.669;1.030) 3581.4 2.194 (-0.029;4.417)   0.017 (0.008;0.025)    
P value <0.001   0.053   <0.001    
  1. Mixed effects model, with random intercept for each patient assessing the association between Ecc-FT, Err-FT and Ecc-SPAMM and the tissue characteristics of each segment. Multivariable model 1 includes segment thickness, LGE and ECV and model 2 includes segment thickness, LGE and native T1. Values denoted in bold are statistically significant with P<0.05. Beta, regression coefficient with 95% confidence interval; BIC, Bayesian information criterion