Blood correction reduces variability and gender differences in native myocardial T1 values at 1.5 T cardiovascular magnetic resonance – a derivation/validation approach

Table 1 Baseline characteristics of the derivation and validation cohorts

Characteristic	Derivation cohort (n = 200)^a	Validation cohort (n = 200)^a	p-value
Age (years)	51 ± 18	48 ± 17	0.14
Female sex, n (%)	100 (50%)	100 (50%)	1.0
Height (cm)	173 ± 14	174 ± 10	0.44
Weight (kg)	77 ± 16	78 ± 18	0.79
BSA (m²)	1.9 ± 0.3	1.9 ± 0.2	0.95
LVEDV (ml)	180 ± 63	183 ± 63	0.56
LVEDVI (ml/m²)	94 ± 29	95 ± 32	0.61
LVESV (ml)	91 ± 57	88 ± 57	0.81
LVESVI (ml/m²)	47 ± 28	46 ± 29	0.95
LVSV (ml)	89 ± 27	95 ± 25	0.02*
LVSVI (ml/m²)	47 ± 14	50 ± 11	0.01*
LVEF (%)	52 ± 12	54 ± 11	0.06
LVM (g)	138 ± 46	137 ± 53	0.75
LVMI (g/m²)	71 ± 19	72 ± 23	0.95
ECV (%)	28 ± 4	28 ± 4	0.51
Hematocrit (%)	40 ± 4	40 ± 5	0.71
Septal wall thickness (mm)	10 ± 2	10 ± 2	0.45
Myocardial T1 (ms)	1030 ± 43	1023 ± 45	0.07
Mean blood R1 (ms⁻¹)	0.00064 ± 0.00004	0.00064 ± 0.00004	0.49
Mean blood R1* (ms⁻¹)	0.00061 ± 0.00005	0.00061 ± 0.00005	0.98

Characteristics are given as means ± standard deviations, or percentages as appropriate. p-values refer to comparison of mean values between derivation and validation cohort. *marks significant result. ^aData missing for LV volumes, EF and mass (n = 2), and ECV (n = 4) in the derivation cohort. Data missing for ECV (n = 2) in the validation cohort

ISSN: 1532-429X