Blood correction reduces variability and gender differences in native myocardial T1 values at 1.5 T cardiovascular magnetic resonance – a derivation/validation approach

Table 4 Correlations and multivariate linear regression coefficients

Characteristic	Univariate r	Multivariate beta	Multivariate beta, final model	Global R²
Derivation cohort (n = 200)				0.26 (p < 0.001)
Hematocrit (%)	−0.37 (p < 0.001)	0.00 (p = 0.98)
Mean blood R1 (ms^-1)	−0.45 (p < 0.001)	−0.28 (p = 0.003)	−0.28 (p = 0.001)
Mean blood R1* (ms^-1)	−0.45 (p < 0.001)	−0.28 (p = 0.002)	−0.28 (p = 0.001)
Septal wall thickness (mm)	0.07 (p = 0.33)	-	-
Validation cohort (n = 200)
Hematocrit (%)	−0.39 (p < 0.001)
Mean blood R1 (ms^-1)	−0.49 (p < 0.001)
Mean blood R1* (ms^-1)	−0.44 (p < 0.001)
Septal wall thickness (mm)	0.07 (p = 0.32)	-	-

All blood measurements correlated with myocardial T1, however hematocrit was not significant in multivariate regression analysis, and therefore not included in the final model.

ISSN: 1532-429X