Fig. 3

Fibrosis and left ventricular function in MESA. The subject without a LGE-defined scar had a relatively lower post contrast T1 time at 25 min with altered regional myocardial shortening and LVEF compared to the subject without an LGE-defined myocardial scar and no evidence of extra-cellular expansion. The subject with a LGE-defined replacement fibrosis had a progressively reduced systolic function. Figures prepared based on data from Donekal et al. [35]. LGE = late gadolinium-enhanced image; LVEF = left ventricular ejection fraction