Table 1 Baseline characteristics of STEMI patients with a CTO, stratified for the randomization outcome, in total group and in patients with serial CMR
Serial CMR (n = 180) | Total (n = 302) | ||||
|---|---|---|---|---|---|
CTO-PCI (n = 80) | No CTO-PCI (n = 100) | CTO-PCI (n = 148) | No CTO-PCI (n = 154) | P-value* | |
Age (years, mean, SD) | 60(10) | 60(10) | 60(10) | 60(10) | 0.81 |
Male gender (%) | 73(91) | 84(84) | 131(89) | 126(82) | 0.25 |
Diabetes (%) | 13(16) | 14(14) | 22(15) | 25(16) | 0.75 |
Hypertension (%) | 30(38) | 48(48) | 59(40) | 69(45) | 0.72 |
Family history of CAD (%) | 32(40) | 38(38) | 66(45) | 64(42) | 0.10 |
Hypercholesterolaemia (%) | 27(34) | 33(33) | 51(35) | 52(34) | 0.81 |
Current smoker (%) | 40(50) | 52(52) | 77(52) | 76(49) | 0.97 |
Previous MI (%) | 9(11) | 17(17) | 19(13) | 24(16) | 1.0 |
Previous PCI (%) | 5(6) | 13(13) | 9(6) | 16(10) | 0.21 |
Previous stroke (%) | 2(3) | 3(3) | 5(3) | 6(4) | 0.36 |
Primary PCI | |||||
Infarct related artery | 0.77 | ||||
Right coronary artery (%) | 26(32) | 31(31) | 46(31) | 47(31) | |
Left circumflex artery (%) | 15(19) | 30(30) | 30(20) | 43(28) | |
Left anterior descending artery/LM (%) | 39(49) | 39(39) | 72(49) | 64(42) | |
Three vessel disease (%) | 34(43) | 42(42) | 62(42) | 67(44) | 0.91 |
MI SYNTAX score I (pre-PCI) | 30(8) | 29(10) | 29(8) | 29(10) | 0.57 |
MI SYNTAX score II (wiring/balloon/aspiration) | 28(8) | 26(10) | 27(8) | 27(10) | 0.62 |
Infarct size | |||||
Peak CK-MB (median, IQR) | 133(38–198) | 87(39–199) | 130(39–272) | 111(43–256) | 0.14 |
Peak Troponin T(median, IQR) | 3.1(1.3–7.8) | 2.9(0.9–5.6) | 3.1(1.1–7.8) | 3.3(0.9–6.0) | 0.23 |
LVEF before randomization a | 41(12) | 42(12) | 41(11) | 42(12) | 0.97 |
CTO characteristics | |||||
Patients with multiple CTOs b | 11(14) | 13(13) | 13(9) | 22(14) | 0.28 |
CTO related artery | 0.61 | ||||
Right coronary artery | 32(40) | 54(54) | 46(43) | 78(51) | |
Left circumflex artery | 23(29) | 24(24) | 48(32) | 37(24) | |
Left anterior descending artery | 25(31) | 22(22) | 36(24) | 39(25) | |
CTO Collaterals Rentrop Grade 2–3 | 48(60) | 53(53) | 80(54) | 82(53) | 0.30 |
Total J-CTO score (mean, SD) | 2.0(1.1) | 2.2(1.1) | 2.1(1.1) | 2.3(1.1) | 0.07 |
Previously failed lesion | 1(1) | 4(4) | 2(1) | 4(3) | 0.41 |
Blunt stump | 17(21) | 27(27) | 33(22) | 45(29) | 0.51 |
Bending | 50(63) | 68(68) | 98(66) | 108(70) | 0.26 |
Calcification | 58(73) | 81(81) | 115(78) | 132(86) | 0.02 |
Occlusion length ≥ 20 mm | 30(38) | 43(43) | 60(40) | 68(44) | 0.48 |