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Table 3 Serial CMR outcomes: Recovery of regional segmental outcomes (SWT), in the total CMR population and according to the territory at risk

From: Improved recovery of regional left ventricular function after PCI of chronic total occlusion in STEMI patients: a cardiovascular magnetic resonance study of the randomized controlled EXPLORE trial

Segmental Wall thickening (%, SD) Total CTO territory IRA territory
All segments CTO PCI
(s = 1184)
No-CTO PCI
(s = 1392)
P-value* CTO-PCI
(s = 392)
No-CTO PCI
(n = 453)
p-value* CTO PCI
(s = 397)
No-CTO PCI
(s = 471)
p-value*
Baseline 41 (34) 43 (34) 44 (35) 40 (33) 31 (28) 33 (31)
4 mo 48 (32) 46 (33) 49 (33) 43 (31) 42 (32) 42 (34)
Absolute difference 7 (30) 4 (30) 5 (31) 3 (28) 0.09 11 (28) 8 (30)
Dysfunctional segments
(SWT Baseline < 45%)
CTO PCI
(s = 722)
No-CTO PCI
(s = 789)
p-value* CTO PCI
(s = 226)
No-CTO PCI
(s = 275)
p-value* CTO PCI
(s = 297)
No-CTO PCI
(s = 316)
p-value*
Baseline 20 (15) 19 (16) 21 (16) 19 (16) 18 (15) 16 (17)
4 mo 36 (28) 31 (25) 0.05 37 (30) 30 (24) 0.02 33 (27) 30 (26)
Absolute difference 16 (26) 13 (24) 0.06 17 (27) 11 (23) 0.03 16 (24) 14 (25)
Dysfunctional and TEI <50% CTO PCI
(s = 574)
No-CTO PCI
(s = 553)
p-value* CTO PCI
(n = 186)
No-CTO PCI
(n = 202)
p-value* CTO PCI
(s = 222)
No-CTO PCI
(s = 206)
p-value*
Baseline 21 (15) 20 (16) 22 (16) 20 (16) 20 (14) 18 (16)
4 mo 38 (28) 33 (25) 0.05 40 (30) 31 (23) 0.01 37 (27) 33 (26)
Absolute difference 16 (26) 13 (24) 0.06 17 (27) 11 (22) 0.02 17 (25) 15 (25)
Dysfunctional and TEI >50% CTO PCI
(s = 36)
No-CTO PCI
(s = 46)
p-value* CTO-PCI
(s = 8)
No-CTO PCI
(s = 7)
p-value* CTO PCI
(s = 27)
No-CTO PCI
(s = 37)
p-value*
Baseline 8 (12) 3 (15) 3 (14) 7 (13) 9 (12) 2 (16)
4 mo 18 (17) 15 (21) 20 (15) 10 (15) 18 (18) 14 (21)
Absolute difference 11 (17) 12 (24) 16 (20) 3 (18) 9 (16) 12 (24)
  1. Data are percentage of segmental wall thickening (± SD)
  2. S number of segments, CMR cardiovascular magnetic resonance, CTO chronic total occlusion, PCI percutaneous coronary intervention, IRA infarct-related artery, SWT segmental wall thickening, TEI transmural extend of infarction
  3. *Outcomes were analyzed using multilevel analysis (linear regression), only p-values ≤0.10 are given