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Table 3 Serial CMR outcomes: Recovery of regional segmental outcomes (SWT), in the total CMR population and according to the territory at risk

From: Improved recovery of regional left ventricular function after PCI of chronic total occlusion in STEMI patients: a cardiovascular magnetic resonance study of the randomized controlled EXPLORE trial

Segmental Wall thickening (%, SD)

Total

CTO territory

IRA territory

All segments

CTO PCI

(s = 1184)

No-CTO PCI

(s = 1392)

P-value*

CTO-PCI

(s = 392)

No-CTO PCI

(n = 453)

p-value*

CTO PCI

(s = 397)

No-CTO PCI

(s = 471)

p-value*

Baseline

41 (34)

43 (34)

44 (35)

40 (33)

31 (28)

33 (31)

4 mo

48 (32)

46 (33)

49 (33)

43 (31)

42 (32)

42 (34)

Absolute difference

7 (30)

4 (30)

5 (31)

3 (28)

0.09

11 (28)

8 (30)

Dysfunctional segments

(SWT Baseline < 45%)

CTO PCI

(s = 722)

No-CTO PCI

(s = 789)

p-value*

CTO PCI

(s = 226)

No-CTO PCI

(s = 275)

p-value*

CTO PCI

(s = 297)

No-CTO PCI

(s = 316)

p-value*

Baseline

20 (15)

19 (16)

21 (16)

19 (16)

18 (15)

16 (17)

4 mo

36 (28)

31 (25)

0.05

37 (30)

30 (24)

0.02

33 (27)

30 (26)

Absolute difference

16 (26)

13 (24)

0.06

17 (27)

11 (23)

0.03

16 (24)

14 (25)

Dysfunctional and TEI <50%

CTO PCI

(s = 574)

No-CTO PCI

(s = 553)

p-value*

CTO PCI

(n = 186)

No-CTO PCI

(n = 202)

p-value*

CTO PCI

(s = 222)

No-CTO PCI

(s = 206)

p-value*

Baseline

21 (15)

20 (16)

22 (16)

20 (16)

20 (14)

18 (16)

4 mo

38 (28)

33 (25)

0.05

40 (30)

31 (23)

0.01

37 (27)

33 (26)

Absolute difference

16 (26)

13 (24)

0.06

17 (27)

11 (22)

0.02

17 (25)

15 (25)

Dysfunctional and TEI >50%

CTO PCI

(s = 36)

No-CTO PCI

(s = 46)

p-value*

CTO-PCI

(s = 8)

No-CTO PCI

(s = 7)

p-value*

CTO PCI

(s = 27)

No-CTO PCI

(s = 37)

p-value*

Baseline

8 (12)

3 (15)

3 (14)

7 (13)

9 (12)

2 (16)

4 mo

18 (17)

15 (21)

20 (15)

10 (15)

18 (18)

14 (21)

Absolute difference

11 (17)

12 (24)

16 (20)

3 (18)

9 (16)

12 (24)

  1. Data are percentage of segmental wall thickening (± SD)
  2. S number of segments, CMR cardiovascular magnetic resonance, CTO chronic total occlusion, PCI percutaneous coronary intervention, IRA infarct-related artery, SWT segmental wall thickening, TEI transmural extend of infarction
  3. *Outcomes were analyzed using multilevel analysis (linear regression), only p-values ≤0.10 are given