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Table 4 Clinical miscategorization of abnormal ECV in the three models

From: Synthetic hematocrit derived from the longitudinal relaxation of blood can lead to clinically significant errors in measurement of extracellular volume fraction in pediatric and young adult patients

  Published Model Static ECV Local Model
  ECVmid-septum ECVmid-free wall ECVmid-septum ECVmid-free wall ECVmid-septum ECVmid-free wall
False Negative 41 (30) 26 (19) 34 (32) 26 (24) 14 (9) 12 (6)
False Positive 4 (8) 3 (2) 3 (3) 1 (2) 12 (11) 8 (6)
Both false negative 14 (9) 12 (12) 6 (2)
Both false positive 1 (0) 1 (0) 3 (3)
Total unique miscategorizations 59 (50) 51 (49) 37 (27)
  1. Using a threshold ECV of 28.5% for abnormal (3 SD), the number of false negatives and false positives were determined for each model
  2. The local model had substantially fewer total miscategorizations, although at the expense of an increased frequency of false positives. Numbers in parentheses are the number of instances in each classification using a threshold of 27.0% (2 SD)