Feature tracking CMR reveals abnormal strain in preclinical arrhythmogenic right ventricular dysplasia/ cardiomyopathy: a multisoftware feasibility and clinical implementation study

Table 2 Right ventricular global (average) strain values stratified by diagnostic group^d

	Overt ARVD/C (N = 39)	Preclinical ARVD/C (N = 40)	Controls (N = 31)	P-Value^c
MEDIS	−17.6 ± 6.3^ab	−21.8 ± 4.6	−21.4 ± 5.5	0.001
TOMTEC	−14.3 ± 7.1^ab	−17.7 ± 6.6	−17.8 ± 5.6	0.057
MTT	−19.3 ± 6.2^ab	−26.2 ± 5.0	−27.7 ± 5.5	<0.001
CIRCLE	−21.3 ± 5.3 ^a	−22.9 ± 3.7	−23.7 ± 2.3	0.065

^a Statistical significant difference compared to control subjects; ^b = Statistical significant difference compared to preclinical subjects; ^c = Trend between overt ARVD/C patients, preclinical ARVD/C and control subjects (OneWay ANOVA). Abbreviations: ARVD/C = Arrhythmogenic Right Ventricular Dysplasia/ Cardiomyopathy; MTT = Multimodality Tissue Tracking; N = number of subjects
^d Segments included based on adequate tracking quality: 365/438, 429/468, and 328/360 segments in overt ARVD/C, preclinical ARVD/C and control subjects respectively

ISSN: 1532-429X