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Table 1 Clinical and angiographic characteristics in patients with change of normal segment ECV per-patient between acute and follow-up scan

From: Extra-cellular expansion in the normal, non-infarcted myocardium is associated with worsening of regional myocardial function after acute myocardial infarction

 

Normal segment

ECV ↓ (n = 22)

Normal segment

ECV ↑ (n = 28)

 

Mean/Median/Count

SD/ 25%–75%/%

Mean/Median/Count

SD/25%–75%/%

p-value

Patient Demographics

Age, yrs

60

11

58

11

0.39

Sex (Male)c

20

40

22

44

0.24

Smokerc

14

28

16

32

0.65

Hypertensionc

5

10

3

6

0.25

Hyperlipidaemiac

9

18

8

16

0.37

Diabetes Mellitusc

4

8

2

4

0.24

Strokec

1

2

0

0

0.26

Presenting Characteristics

Systolic Blood Pressure, mmHg

137

24

134

36

0.88

Heart rate, beats/min

73

14

74

16

0.95

Time from onset of CP to reperfusion, minc

261

158–454

222

149–344

0.43

Heart Failure Killip Classa

Ic

20

40

26

52

0.80

IIc

1

2

2

4

0.70

III-IVc

1

2

0

0

0.26

Ventricular fibrillation at presentationc

0

0

3

6

0.11

Angiographic Characteristics

Number of diseased arteriesb

Single vessel diseasec

16

30

16

32

0.26

Two vessel diseasec

5

10

5

10

0.67

Three vessel diseasec

1

2

7

14

0.05

Culprit Vessel

Left main stemc

0

0

1

2

0.37

Left anterior descendingc

14

28

15

30

0.48

Left circumflexc

2

4

2

4

0.80

Right coronaryc

6

12

11

22

0.38

QRS duration, msecc

90

86–110

94

82–100

0.86

TIMI coronary flow

pre-PCI (<2)c

18

36

26

52

0.15

TIMI coronary flow

post-PCI (<3)c

2

4

2

4

0.77

Laboratory results

White blood cellsc, ×109/l

11

10–15

11

10–13

0.86

Estimated Glomerular Filtration Ratec, ml/min/1.73m2

88

77–90

90

78–90

0.47

Creatine kinasec, U/l

1493

786–2400

1584

867–2570

0.75

Troponinc,

50,000

16,441–50,000

50,000

48,335–50,000

0.34

HBA1cc, mmol/mol

41

36–44

40

36–44

0.77

Infarct characteristics

Infarct size, volume in %

30

17

26

12

0.42

Area at risk, volume in %

49

19

46

17

0.46

Presence of Microvascular Obstruction (MVO)

13

59

16

57

0.89

  1. aKillip classification of heart failure after acute myocardial infarction: class I = no heart failure; class II = pulmonary rales or crepitations, a third heart sound, and elevated jugular venous pressure; class III = acute pulmonary edema; and class IV = cardiogenic shock
  2. bMulti-vessel coronary artery disease was defined according to the number of stenoses of at least 50% of the reference vessel diameter by visual assessment and whether or not there was left main stem involvement
  3. Abbreviations: BMI = body mass index; CMR = cardiac magnetic resonance; CP = chest pain; ECV = extracellular volume; HBA1c = glycated haemoglobin; PCI = percutaneous coronary intervention; STEMI = ST-segment elevation myocardial infarction; TIMI = Thrombolysis In Myocardial Infarction
  4. cNon-normally distributed