Table 3 Overview of study specific cardiac segmentation method, data interpretation, reference standard, cut-off values for significant stenosis and semi-quantitative and/or quantitative analysis
Study | Segmentation | Data interpretation | Reference standard | Cut-off values | Outcome variables |
|---|---|---|---|---|---|
Al-Saadi 2000 [27] | 6 segments (mid ventricular) | Territory | QCA | ≥75% DS | Semi-quantitative |
Bertschinger 2001 [28] | 4 × 8 segments | Patient/Territory | QCA | ≥50% stenosis | Semi-quantitative |
Ibrahim 2002 [29] | 3 short axis slices 18 segments per slice/polar maps subdivided into 6 segments | Territory | QCA | >75% DS | Semi-quantitative |
Nagel 2003 [30] | 5 short axis slices 6 segments per slice | Patient | Visual ICA | ≥75% DS | Quantitative |
Giang 2004 [31] | 3 × 8 segments good quality score | Patient | QCA | ≥50% DS | Semi-quantitative |
Plein 2005 [32] | 16 segments (AHA) | Patient | Visual ICA | >70% DS | Quantitative |
Rieber 2006 [33] | 16 segments (AHA) | Territory | QCA + FFR | >50% DS on QCA and FFR ≤0.75 | Semi-quantitative |
Positano 2006 [34] | 3 short axis slices 16 segments | Segment | QCA | ≥75% DS | Semi-quantitative |
Costa 2007 [35] | 3 short axis 8 segments per slice | Segment | QCA | >70% DS | Quantitaive |
Pignitore 2008 [36] | 3 short axis slices 16 segments | Segment | QCA | ≥50% DS | Semi-quantitative |
KrittayaPhong 2009 [37] | 16 segments (AHA) | Patient | Visual ICA | ≥50% | Semi-quantitative |
Kirschbaum 2011 [38] | 16 segments (AHA) | Patient | ICA with CFR | CFRÂ <Â 2.0 | Semi-quantitative |
Lockie 2011 [39] | 16 segments (AHA) | Territory | FFR | <0.75 | Quantitative |
Bernhardt 2012 [25] | 16 segments (AHA) | Patient | FFR | ≤0.80 | Semi-quantitative |
Huber 2012 [24] | 18 segments (6 per slice) | Territory | QCAÂ +Â FFR | >75% DS on QCA or 51 - 75% DS on QCAÂ +Â FFR <0.75 | Semi-quantitative/Quantitative |
Motwani 2012 [40] | 1 midventricular slice 6 segments | Segment | QCA | >70% DS | Quantitative |
Chiribiri 2013 [41] | 16 segments (AHA) | Territory | FFR | <0.80 | Quantitative |
Mordini 2014 [20] | 3 short axis slices 12 segments per slice | Patient | QCA | >70% DS | Semi-quantitative/Quantitative |
Motwani 2014 [42] | Whole heart | Territory | QCA | ≥75% DS | Quantitative |
Yun 2015 [43] | 16 segments (AHA) | Territory | QCA | >70% DS | Semi-quantitative |
Pan 2015 [44] | 16 segments (AHA) (mean of 2 lowest value assigned to coronary territories) | Territory | FFR | ≤0.75 | Quantitative |
Papanastasiou 2016 [45] | 16 segments (AHA) | Patient/Territory | ICA + FFR | ≥70% DS on ICA or FFR <0.80 and luminal stenosis ≥50% | Quantitative |