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Table 3 Late gadolinium enhancement quantitative results at best time-delays for different gadobutrol doses and its relative comparison

From: High-throughput gadobutrol-enhanced CMR: a time and dose optimization study

Gadobutrol Dose

0.1 mmol/kg

0.2 mmol/kg

 

0.2 mmol/kg (at 20 min) vs. 0.1 mmol/kg (at 10 min)

Time delay

10 min

20 min

COMPARISON

p-value

ICC*

mean difference (LOA)

LGE mass (all patients)

11% (16.4)

12% (14.5)

0.059

0.957

0.9% (7, −5.2)

LGE mass (CAD patients only)

19% (17)

19.8% (20.2)

0.248

0.967

0.2% (6.3, −5.8)

LGE mass (HCM patients only)

7% (6.7)

10.3% (8.4)

0.244

0.876

1.6% (7.6, −4.4)

  1. * p < 0.001 for all ICC values, CAD Coronary artery disease, HCM Hypertrophic cardiomyopathy, LGE Late gadolinium enhancement, LOA Limits of agreement