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Table 2 Univariate Cox-regression for overall survival or heart transplantation (n = 68)

From: Regional differences in prognostic value of cardiac valve plane displacement in systemic light-chain amyloidosis

Variable X2 HR 95% CI p
NYHA class 7.5 1.75 1.15 to 2.68 0.001
Karnofsky Index 21.3 0.91 0.88 to 0.95 0.0001
CMR parameters
 AAPSE (mm) 15.6 0.10 0.03 to 0.34 0.0002
 MAPSE anterior (mm) 8.1 0.19 0.06 to 0.60 0.004
 MAPSE anterolateral (mm) 11.7 0.23 0.10 to 0.56 0.001
 MAPSE inferolateral (mm) 6.2 0.36 0.16 to 0.83 0.02
 MAPSE inferior (mm) 9.0 0.26 0.10 to 0.63 0.003
 MAPSE inferoseptal (mm) 7.7 0.26 0.10 to 0.68 0.01
 TAPSE (mm) 6.7 0.94 0.90 to 0.99 0.01
 GLS (%) 11.7 1.12 1.05 to 1.19 0.0006
 LSbasal (%) 8.3 1.08 1.02 to 1.13 0.006
 LSmid (%) 12.8 1.13 1.06 to 1.21 0.0005
 LSapical (%) 6.9 1.07 1.02 to 1.12 0.005
 Ejection Fraction (%) 11.6 0.95 0.93 to 0.98 0.0007
 Septal wall (mm) 0.7 1.03 0.96 to 1.11 n.s.
 Relative LV Mass (g/m2) 1.8 1.01 0.99 to 1.02 n.s.
 LA dilation a 0.02 1.05 0.55 to 1.97 n.s.
 Relative LGE (%) 4.4 1.02 1.00 to 1.04 0.03
 Qualitative LGE (n) 6.8 1.50 1.09 to 2.06 0.009
Laboratory data
 cTNT ULN a 5.3 1.94 1.09 to 3.45 0.02
 log NT-proBNP (pg/mL) 13.0 1.52 1.20 to 1.94 0.0006
 MDRD (mL/min/1.73m2) 0.2 1.00 0.99 to 1.01 n.s.
 log FLC difference (mg/dL) 6.3 1.71 1.10 to 2.65 0.02
  1. X 2 chi square, HR hazard ratio, CI confidence interval, adichotomous variable
  2. AAPSE anterior aortic plane systolic excursion, MAPSE mitral annular plane systolic excursion, TAPSE tricuspid annular plane systolic excursion, GLS global longitudinal strain, LS basal mean longitudinal strain of basal segments 1-6, LS mid mean longitudinal strain of midventricular segments 7-12, LS apical mean longitudinal strain of apical segments 13-16, LA left atrium, relative LGE proportion of late gadolinium enhancement quantified by 5SD method, qualitative LGE late gadolinium enhancement graduated in (1) none, (2) subendocardial or (3) transmural involvement, cTNT ULN cardiac troponin T upper limit of normal, NT-proBNP N-terminal prohormone of brain natriuretic peptide, MDRD glomerular filtration rate calculated with the formula of “Modification of Diet in Renal Disease”, FLC free light chain difference
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