Fig. 1
Proposed post-contrast BOOST framework for simultaneous 3D whole-heart bright-blood coronary angiography and black-blood late gadolinium enhancement (LGE) assessment. A T2-prepared inversion recovery (T2Prep-IR) module is applied at odd heartbeats (T2Prep-IR BOOST, magnitude image) (a), whereas data acquisition is T2 prepared and performed with a high flip angle at even heartbeats (bright-blood T2Prep-BOOST, reference image) (b). A 3D Cartesian trajectory with spiral profile order [28] is used for data acquisition; data collection is segmented over multiple heartbeats (yellow, red, blue) to minimize the effects of cardiac motion. Even heartbeat acquisitions include a SPIR pulse for fat saturation, while a STIR-like fat suppression is employed in odd heartbeats. 3D data acquisition at each heartbeat is preceded by a low-resolution 2D image-based navigator (iNAV) that is used to estimate translational respiratory motion along the superior-inferior and right-left directions. The two motion corrected datasets (T2Prep-IR BOOST and T2Prep BOOST) are combined in a PSIR-like reconstruction to generate a third, complementary, black-blood dataset (PSIR BOOST) for LGE visualization (c). The motion corrected bright-blood T2Prep BOOST dataset (reference image, b) provides adequate contrast for heart anatomy, great vessel, and coronary lumen visualization