Table 4 Multivariate cox-proportional hazards models
From: Cardiac amyloidosis is prevalent in older patients with aortic stenosis and carries worse prognosis
Model 1 (X2 = 43.8, P < 0.0001) | Model 2 (X2 = 53.2, P < 0.0001) | Model 3 (X2 = 51.7, P < 0.0001) | |||||||
|---|---|---|---|---|---|---|---|---|---|
HR | 95% CI | P value | HR | 95% CI | P value | HR | 95% CI | P value | |
Cardiac amyloid (vs. No Cardiac amyloid) | 2.80 | (1.05, 7.5) | 0.04 | 2.84 | (1.07, 7.56) | 0.037 | 2.95 | (1.08–8.03) | 0.035 |
Any AVR (vs. Medical therapy) | 0.29 | (0.15, 0.58) | < 0.001 | 0.33 | (0.16, 0.65) | 0.001 | 0.22 | (0.11, 0.46) | < 0.001 |
STS PROM (per 1%) | 1.16 | (1.09, 1.24) | < 0.001 | 1.17 | (1.09, 1.26) | < 0.001 | 1.15 | (1.07, 1.23) | < 0.001 |
CMR LVEF (per 1%) | – | – | – | 0.97 | (0.95, 0.98) | < 0.001 | – | – | – |
NYHA Class ≥ III at presentation | – | – | – | – | – | – | 3.63 | (1.68, 7.82) | 0.001 |