The prognostic value of T1 mapping and late gadolinium enhancement cardiovascular magnetic resonance imaging in patients with light chain amyloidosis

Table 3 T1 mapping intra-observer and inter-observer variabilities and native T1 reproducibility showed by Bland-Altman Plot

	Bias	SD of bias	95% CI
Native T1
Intra-observer variability 1/ms	−5.60	16.40	−37.04, 25.84
Intra-observer variability 2/ms	4.20	19.74	−34.49, 42.89
Inter-observer variability/ms	6.12	18.33	−32.88, 44.51
Repeated scan reproducibility/ms	5.45	21.07	−35.86, 46.76
ECV
Intra-observer variability 1/%	0.33	1.44	−2.96, 3.02
Intra-observer variability 2/%	0.27	1.87	−2.41, 3.15
Inter-observer variability 1/%	−0.25	1.82	−3.36, 2.80

Repeated pre-contrast T1 mapping scans were performed within one day on 20 volunteers (native T1, 1283 ± 46 ms; LVEF, 65.4 ± 5.7%) and 20 patients (Mayo Stage I/II/III/IV, n = 4/6/8/2; none/patchy/global LGE, n = 6/4/10; native T1, 1498 ± 108 ms; LVEF, 58.6 ± 11.1%). For all patients and volunteers, T1 mapping images were independently analyzed by two experienced radiologists twice. The average value was used. SD Standard deviation, CI Confidence interval, ECV Extracellular volume

ISSN: 1532-429X