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Table 4 Native T1, ECV and LGE correlation with clinical stages, echocardiographic and other cardiac MR parameters in AL amyloidosis patients

From: The prognostic value of T1 mapping and late gadolinium enhancement cardiovascular magnetic resonance imaging in patients with light chain amyloidosis

 

Native T1

ECV

LGE

r or ρ

P

r or ρ

P

ρ

P

Clinical

 NYHA

0.427

0.001

0.686

0.001

0.674

0.001

 NT-proBNP

0.351

0.001

0.707

0.001

0.729

0.001

 Mayo Stage

0.335

0.002

0.631

0.001

0.671

0.001

Echocardiography

 E/A

0.060

0.65

0.309

0.20

0.330

0.20

 E/E’

0.302

0.209

0.488

0.001

0.351

0.006

Cardiac MR

 Indexed LVEDV

−0.222

0.025

−0.320

0.001

−0.113

0.31

 Indexed LVESV

−0.078

0.44

0.209

0.036

0.203

0.067

 LVEF

0.063

0.93

−0.451

0.001

−0.380

0.001

 Left atrium area

0.207

0.037

0.174

0.082

0.197

0.077

 Indexed left ventricle mass

0.360

0.001

0.633

0.001

0.590

0.001

 Septal thickness

0.440

0.001

0.626

0.001

0.654

0.001

 Native T1

0.605

0.001

 LGE

0.420

0.001

0.867

0.001

  1. Correlation between native T1 or ECV with continuous variables was assessed using Pearson’s r correlation and with categorical variables using Spearman ρ correlation. Correlation between LGE with other variables was assessed using Spearman ρ correlation
  2. NYHA New York Heart Association, NT-proBNP N-terminal pro-B-type natriuretic peptide, MR Magnetic resonance, LVEDV Left ventricle end-diastolic volume, LVESV Left ventricle end-systolic volume, LVEF Left ventricle ejection fraction, LGE Late gadolinium enhancement, ECV Extracellular volume