Skip to main content

Table 1 Baseline Characteristics of the Study Population

From: Non-invasive differentiation of idiopathic inflammatory myopathy with cardiac involvement from acute viral myocarditis using cardiovascular magnetic resonance imaging T1 and T2 mapping

  Healthy controls (n = 20)   Acute viral myocarditis (n = 20) IIM with inflammatory myocarditis (n = 20) p - value
Age, years 47 ± 12   35 ± 13* 54 ± 18 < 0.001
Male / Female 9 / 11   16 / 4* 9 / 11 0.048
BMI, kg/m2 25 ± 4   24 ± 6 22 ± 3 0.286
Heart failure 0 (0%)   2 (10%) 1 (5%) > 0.999
Atrial fibrillation or AV block 0 (0%)   4 (20%) 5 (25%)* 0.725
Significant valvulopathy 0 (0%)   0 (0%) 0 (0%)  
Dyspnea 0 (0%)   2 (10%) 6 (30%)* 0.235
Chest pain 0 (0%)   19 (95%)* 2 (10%) < 0.001
Dysphagia 0 (0%)   0 (0%) 2 (10%) 0.487
Myalgia 0 (0%)   0 (0%) 7 (35%)* 0.008
Muscle weakness 0 (0%)   0 (0%) 19 (95%)* < 0.001
Arterial hypertension 0 (0%)   3 (15%) 3 (15%)  
Dyslipidemia 0 (0%)   2 (10%) 5 (25%) 0.408
Diabetes 0 (0%)   0 (0%) 2 (10%) 0.487
Immunosuppressive treatment 0 (0%)   0 (0%) 20 (100%)* < 0.001
Duration of disease, months 0 ± 0   0.17 ± 0.13 57 ± 53 0.001
NT-proBNP, pg/ml N/A   1636 ± 3800 699 ± 1226 0.077
Troponin T, ng/ml N/A   647 ± 610 583 ± 651 0.507
CPK, IU/l N/A   256 ± 197 2438 ± 3547 0.001
Hematocrit, % 42 ± 3   38 ± 5* 40 ± 3 0.554
Creatinine, μmol/l 82 ± 14   86 ± 53 50 ± 20* < 0.001
CRP mg/l 1.3 ± 1.3   36 ± 54* 15 ± 25* 0.093
  1. Values are mean ± SD or n (%). *p < .05 compared to controls, p-values of the direct comparison between acute viral myocarditis and IIM myocarditis are shown in the last column, using Mann-Whitney U or Fisher’s exact test, as appropriate
  2. AV atrio-ventricular, IIM idiopathic inflammatory myopathy, BMI body-mass-index, CPK creatine phosphokinase, CRP c-reactive protein, NT-proBNP N-terminal pro b-type natriuretic peptide
\