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Table 3 CMR Mapping Parameters

From: Non-invasive differentiation of idiopathic inflammatory myopathy with cardiac involvement from acute viral myocarditis using cardiovascular magnetic resonance imaging T1 and T2 mapping

  Healthy controls (n = 20) Acute viral myocarditis (n = 20) IIM with inflammatory myocarditis (n = 20) p-value / age adjusted p-value
Myocardium including LGE positive segments
 T1 native, ms 965 ± 25 1044 ± 63*/* 1017 ± 43*/* 0.121
 T1 contrast 15 min, ms 379 ± 54 320 ± 34*/* 326 ± 54*/* 0.925
 ECV, % 22 ± 3 24 ± 7*/* 23 ± 3 0.134
 T2, ms 48 ± 2 53 ± 4*/* 53 ± 3*/* 0.758
Myocardium excluding LGE positive segment
 T1 native, ms 965 ± 25 1023 ± 52*/* 1011 ± 36*/* 0.445
 T1 contrast 15 min, ms 379 ± 54 330 ± 38*/* 328 ± 51*/* 0.718
 ECV, % 22 ± 3 25 ± 3*/* 23 ± 4 0.351
 T2, ms 48 ± 2 51 ± 3*/* 52 ± 3*/* 0.174
Skeletal Muscles
 T1 native, ms 842 ± 39 844 ± 62 963 ± 127*/* 0.001 / 0.002
 T1 contrast 15 min, ms 510 ± 43 482 ± 39*/* 374 ± 55*/* < 0.001 / < 0.001
 ECV, % 10 ± 2 10 ± 3 19 ± 7*/* < 0.001 / < 0.001
 T2, ms 40 ± 2 38 ± 2* 45 ± 10 < 0.001 / 0.022
  1. Values are mean ± SD. */* p < .05 compared to controls without / with age adjustment. p-values/age adjusted p-values of the direct comparison between acute viral myocarditis and IIM myocarditis are shown in the last column, using Mann-Whitney U test and a multivariate regression model. Age adjusted p-values were only calculated in case of significant non-adjusted p-values
  2. IIM idiopathic inflammatory myopathy, ECV extracellular volume fraction, SD Standard deviation
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