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Table 3 Ascending aortic flow pattern parameters by aortic valve replacement subgroup

From: Differential flow improvements after valve replacements in bicuspid aortic valve disease: a cardiovascular magnetic resonance assessment

  Healthy Subjects  n = 30 BAV- native n = 30 AVR-mechanical n = 11 AVR-tissue n = 10 Ross n = 9 ANOVA
Age in years 43 ± 17 42 ± 16 42 ± 12 58 ± 11 24 ± 12 p < 0.001
Systolic flow angle (°) 7.5 ± 5.3 25.6 ± 13.3* 16.5 ± 9.6 16.2 ± 8.5 9.8 ± 4.9† p < 0.001
Normalised flow displacement 0.038 ± 0.036 0.133 ± 0.072* 0.083 ± 0.076 0.163 ± 0.064* 0.096 ± 0.067 p < 0.001
Absolute rotational flow (mm2/ms) 3.8 ± 3.1 26.6 ± 16.6* 7.2 ± 3.9† 20.7 ± 8.8* 10.6 ± 10.5† p < 0.001
Mean systolic WSScircavg (N/m2) 0.58 ± 0.15 0.77 ± 0.23* 0.67 ± 0.20 0.68 ± 0.20 0.80 ± 0.35 p = 0.012
Absolute systolic in-plane (rotational) WSS (N/m2) 0.07 ± 0.06 0.40 ± 0.28* 0.19 ± 0.13† 0.38 ± 0.19* 0.21 ± 0.17 p < 0.001
Max systolic through-plane WSS (N/m2) 0.76 ± 0.21 0.95 ± 0.44 0.91 ± 0.38 0.78 ± 0.215 1.03 ± 0.65 p = 0.206
RA-LP systolic WSScircavg (N/m2) −0.12 ± 0.13 0.22 ± 0.31* 0.27 ± 0.22* 0.36 ± 0.26* 0.24 ± 0.67 p < 0.001
Peak velocity (m/s) 2.3 ± 0.8 2.1 ± 0.5 2.1 ± 0.3 1.9 ± 0.8 p = 0.387
Ascending aortic diameter (mm) 28.6 ± 4.3 35.0 ± 6.7* 35.9 ± 4.4* 37.9 ± 5.2* 30.4 ± 8.3 p < 0.001
Diameter at sino-tubuar junction (mm) 27.9 ± 3.6 32.4 ± 6.4* 31.7 ± 7.8 32.9 ± 3.3 31.0 ± 6.0 p = 0.003
Diameter at sinuses (mm) 30.8 ± 3.5 32.9 ± 5.8 34.1 ± 6.7
(pre-AVR)
32.1 ± 2.3
(pre-AVR)
35.9 ± 5.7 p = 0.068
Aortic regurgitant fraction (%) 8.8 ± 9.9 3.7 ± 2.8 5.8 ± 7.5 22.8 ± 20.6† p = 0.002
Left ventricular ejection fraction (%) 68 ± 6 67 ± 15 70 ± 8 65 ± 10 p = 0.687
  1. Values are mean ± standard deviation except where indicated; * = p < 0.05 compared to healthy volunteers; † = p < 0.05 compared to native BAV; BAV = bicuspid aortic valve; AVR = aortic valve replacement; WSS = wall shear stress; WSScircavg = circumferentially averaged wall shear stress; RA-LP = right anterior – left posterior