Fully quantitative pixel-wise analysis of cardiovascular magnetic resonance perfusion improves discrimination of dark rim artifact from perfusion defects associated with epicardial coronary stenosis

Table 2 Summary of coronary artery disease status, hemodynamics, and CMR findings

	NonCAD (N = 55)		CAD (N = 21)		p-value
Extent of CAD by QCA
Left main disease	N/A		0	0%	N/A
LAD disease	N/A		16	76%	N/A
CX disease	N/A		9	43%	N/A
RCA disease	N/A		12	57%	N/A
3-vessel CAD^a	N/A		0^a	0%^a	N/A
2-vessel CAD	N/A		16	76%	N/A
1-vessel CAD	N/A		5	24%	N/A
Severity of stenosis
0–49%	N/A		47	56%	N/A
50–69%	N/A		13	15%	N/A
≥ 70%	N/A		24	29%	N/A
Hemodynamics
Baseline systolic BP (mmHg)	131.3 ± 14.7		137.0 ± 12.7		0.122
Baseline diastolic BP (mmHg)	79.5 ± 10.7		78.3 ± 13.3		0.875
Baseline heart rate (bpm)	67.1 ± 12.1		66.7 ± 10.7		0.891
Baseline rate pressure Product (bpm^ammHg)	9148 ± 1784		8802 ± 1785		0.452
Stress systolic BP (mmHg)	128.8 ± 17.7		134.2 ± 16.7		0.224
Stress diastolic BP (mmHg)	74.5 ± 14.2		72.3 ± 14.5		0.548
Stress heart rate (bmp)	101.2 ± 14.0		94.7 ± 13.7		0.070
Stress rate pressure product (bmp^ammHg)	12,709 ± 2472		13,053 ± 2743		0.617
CMR Findings
LV ejection fraction (%)	64.1 ± 6.5		60.3 ± 6.5		0.047
LV stroke volume (ml)	100.4 ± 21.7		93.1 ± 25.0		0.213
LVEDV (ml)	159.2 ± 41.8		157.0 ± 45.1		0.841
LVESV (ml)	58.7 ± 25.5		63.9 ± 29.1		0.453
LVED Mass (g)	98.0 ± 28.8		107.7 ± 25.5		0.177
LGE evidence of infarction	0	0%	8	38%	< 0.001

Abbreviations: BP blood pressure, CX circumflex coronary artery, LGE late gadolinium enhancement, LV left ventricular, LVEDV left ventricular end diastolic volume, LVESV left ventricular end systolic volume, LVEDMass left ventricular end diastolic mass, LGE late gadolinium enhancement, N/A not applicable
p values that were significant (p<0.050 or lower) are in bold
^aPatients with a prior history of coronary artery by-pass surgery and 3 vessel CAD coronary artery disease were excluded from this study

ISSN: 1532-429X