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Fig. 2 | Journal of Cardiovascular Magnetic Resonance

Fig. 2

From: Association between myocardial extracellular volume and strain analysis through cardiovascular magnetic resonance with histological myocardial fibrosis in patients awaiting heart transplantation

Fig. 2

Representative histological analysis of patients undergoing heart transplantation. The whole-heart tissue samples were stained with picrosirius red (red = collagen, yellow = myocytes). Examples show mild (a, collage volume fraction (CVF) = 12.0%), moderate (b, CVF = 26.3%) and extensive fibrosis (c, CVF = 43.2%). The total myocardial area (d) and collagen area marked with black (e) were calculated semi-automatically using Image-Pro Plus software. Panel (f) shows the red collagen alone. The CVF was defined as the percentage of collagen area divided by the total myocardial area

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