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Table 5 Summary of literature on MBF repeatability

From: Fully automated, inline quantification of myocardial blood flow with cardiovascular magnetic resonance: repeatability of measurements in healthy subjects

 

Rest

Stress

MPR

 

Author

Year

n

T test

r/ICC

RC

(%)

CV

(%)

T test

r/ICC

RC

(%)

CV

(%)

T test

r/ICC

RC

(%)

CV

(%)

Immediate (intrastudy)

PET

Nitzsche [30]

1996

15

0.33

0.99

33

 

0.16

0.97

13

     

Kaufmann [14]

1999

21

ns

 

18

 

ns

 

25

 

ns

 

33

 

Wyss [23]

2003

11

ns

0.77

21

  

0.77

27

 

ns

0.74

35

 

Schindler [31]

2007

20

 

0.72

29

  

0.76

20

     

Manabe [15]

2009

15

0.31

 

22

 

0.81

 

27

 

0.53

 

37

 

Kitkungvan [18]

2017

120

0.93

  

11

0.74

  

10

    

Ocneanu [19]

2017

12

   

21

   

15

    

CMR

Keitha [32]

2017

10

  

53

13

        

This study

  

0.08

0.8

24

8

0.41

0.76

29

11

    

Delayed (interstudy)

PET

Nagamachi [16]

1996

30

ns

0.63

31

 

ns

0.69

18

   

20

 

Schindler [31]

2007

20

 

0.75

30

  

0.71

23

     

Sdringola [17]

2011

48

p < 0.05

0.68

35

 

ns

0.53

34

 

ns

0.47

38

 

Johnson [24]

2015

50

0.46

 

41

 

0.13

 

34

 

0.29

 

34

 

Kitkungvan [33]

2017

19

0.13

   

0.94

  

17

0.26

  

20

Kitkungvan [18]

2017

120

0.13

  

21

0.81

  

19

    

CMR

Jerosch-Herold [20]

2008

30

0.001

 

30

 

0.11

 

41

     

Larghata [8]

2013

11

0.2

 

45

20

0.61

 

73

40

0.11

 

69

35

Likhite [21]

2016

10

 

0.77

       

0.88

  

Keitha [32]

2017

10

  

61

16

        

This study

  

0.8

0.74

32

11

0.12

0.72

33

12

0.25

0.44

36

13

  1. ns not significant (p value not reported), r Pearson correlation coefficient, RC reproducibility coefficient (% of mean), CV coefficient of variation
  2. aRepeatability data is given for single mid-ventricular slice, all other studies, data is for global myocardium, averaged from multiple slices. Where RC was not published, but sufficient data was provided, this has been calculated using 1.96*SD of difference. Similarly, all RC are given as % for ease of comparison