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Table 2 Comparison of cardiac MRI parameters between groups

From: Myocardial native T2 measurement to differentiate light-chain and transthyretin cardiac amyloidosis and assess prognosis

MRI parameters

AL (n = 24)

ATTR (n = 20)

Healthy subjects (n = 40)

p*

LV EDV (mL/m2)

74 ± 23

89 ± 27

77 ± 16

0.06£

LV ESV (mL/m2)

35 ± 21

47 ± 28

27 ± 9

0.1$

IVS (mm)

17 ± 3

18 ± 3

9 ± 2

0.3

LV mass (g/m2)

97 ± 28

115 ± 31

63 ± 11

0.04$

LVEF (%)

56 ± 18

50 ± 19

65 ± 8

0.3$

Native T1 (ms)

1104 ± 54

1066 ± 42

975 ± 26

0.01$

Native T2 (ms)

63.2 ± 4.7

56.2 ± 3.1

51.1 ± 3.1

0.0001$

T2 ratio

1.31 ± 0.4

1.41 ± 0.2

1.44 ± 0.3

0.2

Post contrast T1 (ms)

378 ± 73

363 ± 69

NA

0.9

ECV

0.53 ± 0.17

0.46 ± 0.11

NA

0.2

ICV

0.47 ± 0.17

0.54 ± 0.11

NA

0.2

T. amyloid vol. (mL/m2)

57 ± 27

53 ± 22

NA

0.7

T. cell vol. (mL/m2)

47 ± 15

61 ± 19

NA

0.04

  1. *: AL vs. ATTR patients
  2. $: p < 0.005: Healthy subjects and CA patients
  3. £: p = 0.4: Healthy subjects and CA patients