Fig. 2

Example of left ventricular (LV) high resolution CMR segmentation and corresponding eosin stained histological images. a-b: Example of a midventricular short axis, cine image from a mutant mouse heart (a) and slice at the same level from eosin stained histological slide (b). c-d: Semi-automatic LV segmentation of the cine image: the epicardial border appears in blue, the endocardial border in red, the trabecular border in green (c) and the trabecular surface in green (d). The papillary muscles were segmented and included in the compacted area (yellow line) (c). e: Manual LV segmentation of the histological slice using the same segmentation procedure: epicardial border in blue, endocardial border in red, trabecular border in green. The papillary muscles were segmented and included in the compacted area (yellow line)