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Fig. 5 | Journal of Cardiovascular Magnetic Resonance

Fig. 5

From: Quantitative myocardial first-pass cardiovascular magnetic resonance perfusion imaging using hyperpolarized [1-13C] pyruvate

Fig. 5

Simulation results for variations of myocardial blood flow (MBF) in units of mL/g/min for SNR = 7.5, 15 and 30. a Calculated MBF after reconstruction vs. simulated MBF value. Reference values used to calculate input concentration dynamics are indicated by the solid line. Dotted lines indicate the ±25% interval around the reference value. Simulated MBF values ≤1.0 result in overestimation for all SNR levels, whereas higher simulated MBF values are only underestimated for lower SNR levels. b-c Semi-quantitative perfusion measures as function of absolute MBF values analogous to Fig. 3. The dotted line represents the linear regression model calculated at SNR = 50 (top left corner). b Myocardial upslope (SLP). c Area under the curve (AUC). d Mean absolute MBF quantification with relative error per myocardial sector for SNR = 15. Strong overestimation at low MBF values, and moderate underestimation at high MBF values is apparent

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