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Table 1 Anthropometrics and baseline descriptives in Turner syndrome and age and gender-matched controls, and Turner syndrome without CoA (Coarctation of Aorta) and Turner syndrome with CoA

From: Impaired aortic distensibility and elevated central blood pressure in Turner Syndrome: a cardiovascular magnetic resonance study

  Turner Syndrome (n = 57) Controls (n = 36) P value† Turner Syndrome without CoA (n = 49) Turner Syndrome with CoA (n = 8) P value‡
Age [years] 46.1 ± 10.2 46.0 ± 12.9 0.9 45.9 ± 10.2 47.1 ± 10.3 0.8
Weight [kg] 62.5 ± 14.6 71.2 ± 13.5 0.01 61.8 ± 14.3 66.9 ± 16.4 0.4
Height [cm] 147.2 ± 6.7 169.3 ± 6.4 < 0.001 147.0 ± 7.1 148.1 ± 3.8 0.7
Body Mass Index [kg/m2] 28.9 ± 6.7 24.9 ± 4.6 0.001 28.6 ± 6.6 30.5 ± 7.3 0.5
Body Surface Area 1.5 ± 0.2 1.8 ± 0.2 < 0.001 1.5 ± 0.2 1.6 ± 0.2 0.4
24 h systolic Blood Pressure [mmHg]a 117.9 ± 12.7 115.2 ± 10.7 0.3 117.5 ± 13.0 120.1 ± 11.6 0.6
24 h diastolic Blood Pressure [mmHg]a 74.5 ± 10.2 71.7 ± 6.6 0.1 74.3 ± 9.9 75.3 ± 12.5 0.8
Day-time systolic Blood Pressure [mmHg]a 123.4 ± 13.5 121.4 ± 10.6 0.5 122.8 ± 13.5 126.6 ± 14.2 0.5
Day-time diastolic Blood Pressure [mmHg]a 78.6 ± 11.4 76.9 ± 6.5 0.4 78.3 ± 10.7 80.3 ± 15.1 0.7
Night-time systolic Blood Pressure [mmHg]a 106.4 ± 11.9 103.3 ± 11.1 0.2 106.4 ± 12.6 106.4 ± 8.2 1
Night-time diastolic Blood Pressure [mmHg]a 66.2 ± 8.6 61.5 ± 7.1 0.01 66.3 ± 8.7 65.6 ± 8.9 0.9
Systolic Blood pressure, Sphygmocor (right) 121.3 ± 12.9 119.4 ± 13.8 0.5 120.7 ± 13.3 125.1 ± 10.0 0.4
Diastolic Blood pressure, Sphygmocor (right) 77.6 ± 9.8 72.1 ± 8.8 0.007 77.3 ± 10.1 79.4 ± 8.8 0.6
Systolic Blood pressure, Sphygmocor (left) 118.2 ± 13.8 118.4 ± 14.0 1.0 117.8 ± 14.3 120.6 ± 10.1 0.6
Diastolic Blood pressure, Sphygmocor (left) 76.3 ± 9.4 71.3 ± 9.0 0.01 76.2 ± 9.4 77.1 ± 10.3 0.8
Low Density Lipids [mmol/L]b 2.6 ± 0.8 2.6 ± 0.9 0.9 2.7 ± 0.8 2.6 ± 0.9 0.9
High Density Lipids [mmol/L]b 1.8 ± 0.6 1.8 ± 0.5 0.8 1.8 ± 0.5 1.7 ± 0.7 0.9
Triglycerides [mmol/L]b 1.1 ± 0.7 1.1 ± 1.0 0.8 1.1 ± 0.6 1.4 ± 0.9 0.2
HbA1C [mmol/mol]b 36.0 [28.0–70.0] 35.5 [26.0–48.0] 0.2 36.0 [28.0–62.0] 38.4 [31.0–70.0] 0.3
Bicuspid aortic valvec 19% (11/57) 0% (0/36) 0.006 12% (6/49) 63% (5/8) 0.005
Coarctation of the aortac 14% (8/57) 0% (0/36) 0.02 0% (0/49) 100% (8/8) < 0.001
Elongated transverse aortac 46% (26/57) 0% (0/36) < 0.001 43% (21/49) 63% (5/8) 0.3
Type 2 Diabetesc 18% (10/57) 0% (0/36) 0.006 12% (6/49) 50% (4/8) 0.03
Statinsc 16% (9/57) 3% (1/36) 0.08 14% (7/49) 25% (2/8) 0.4
Aspirinc 5% (3/57) 0% (0/36) 0.3 6% (3/49) 0% (0/8) 0.6
Antihypertensivesc 49% (28/57) 14% (5/36) < 0.001 49% (24/49) 50% (4/8) 0.6
Hormone replacement treatmentc 72% (41/57) 3% (1/36) < 0.001 73% (36/49) 63% (5/8) 0.4
  1. Blood pressure marked with SphygmoCor where used to calibrated measurements done with the SphygmoCor equipment
  2. afor Turner syndrome: n = 50, for controls: n = 34. For Turner syndrome without CoA: n = 42
  3. bfor Turner syndrome: n = 56, for controls: n = 36. For Turner syndrome without CoA: n = 48
  4. cFisher’s Exact Test
  5. †: p-value for the comparison between the entire TS cohort and controls
  6. ‡: p-value for the comparison between TS without CoA and TS with CoA