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Table 1 Baseline characteristics of kidney transplant and dialysis patients

From: Cardiovascular magnetic resonance left ventricular strain in end-stage renal disease patients after kidney transplantation

Characteristic Dialysis patients (n = 40) Kidney transplant patients (n = 39) P value
Age, years, mean (s.d.) 56 (11) 47 (12) 0.001
Sex, male 28 (70) 27 (69) 0.57
BMI, kg/m2, mean (s.d.) 26.7 (4.8) 26.0 (4.6) 0.60
Cardiovascular risk factors, n (%)
 Hypertension 37 (93) 36 (92) 0.65
 Diabetes 17 (43) 11 (28) 0.14
 Dyslipidemia 34 (85) 27 (69) 0.080
 Current smoking 4 (10) 2 (5.1) 0.68
Cardiovascular disease
 Myocardial infarction 4 (10) 2 (5.1) 0.35
 Stroke 3 (7.5) 0 (0) 0.13
 Heart failure 2 (5.0) 1 (2.6) 0.51
 Percutaneous coronary intervention or bypass surgery 4 (10) 4 (10) 1.00
Dialysis vintage, months, median (IQR) 24 (15–42) 14 (9–28) 0.028
Cause of end-stage renal disease    0.052
 Diabetes 16 (40) 9 (23)  
 Hypertension 3 (7.5) 3 (7.7)  
 Glomerulonephritis 12 (30) 8 (20)  
 Polycystic kidney disease 2 (5.0) 9 (23)  
 Interstitial nephritis 2 (5.0) 3 (7.7)  
 Congenital anomalies 1 (2.5) 3 (7.7)  
 Other/unknown 4 (10) 4 (10)  
Cardiovascular medications, n (%)
 Beta-blockers 19 (48) 21 (54) 0.37
 ACE inhibitors 10 (25) 10 (26) 0.58
 ARB 14 (35) 11 (28) 0.34
 CCB 17 (43) 24 (62) 0.071
 Diuretic 15 (38) 11 (28) 0.26
 Statin 29 (73) 17 (44) 0.008
 Fibrate 0 (0) 1 (2.6) 0.49
 Ezetimibe 3 (7.5) 2 (5.1) 0.51
 Aspirin 17 (43) 11 (28) 0.14
Blood pressure, mean (s.d.)
 Systolic blood pressure, mmHg 130 (29) 130 (18) 0.33
 Diastolic blood pressure, mmHg 77 (13) 81 (12) 0.12
 Heart rate, bpm, mean (s.d.) 72 (13) 75 (13) 0.56
Baseline serum measurements, median (IQR)
 Creatinine, μmol/L 715 (559–840) 787 (568–925) 0.38
 N-Terminal brain natriuretic peptide, ng/mL 1487 (741–2535) 889 (554–1368) 0.28
 Hemoglobin, g/L 114 (105–129) 119 (109–127) 0.54
 C-reactive protein, ng/mL 2.9 (1.9–7.6) 1.5 (1.0–4.2) 0.019
 Growth differentiation factor-15, pg/mL 5440 (4307–6452) 4744 (3639–5784) 0.13
 PTH, pmol/mL 32 (18–67) 36 (19–79) 0.79
Cardiovascular magnetic resonance parameters, mean (s.d.)
 LVEDVi (mL/m2) 84 (22) 94 (24) 0.038
 LVESVi (mL/m2) 34 (13) 40 (15) 0.043
 LVEF (%) 59.8 (6.6) 57.6 (6.4) 0.13
 LVMi (g/m2) 65.1 (20) 66.7 (20) 0.78
 Cardiac index (L/min/m2) 3.49 (0.9) 3.96 (0.9) 0.024
 GLS (%) −16.6 (3.2) −15.9 (3.0) 0.44
 GCS (%) −19.7 (3.6) −18.1 (3.4) 0.057
 GRS (%) 46.1 (13) 40.8 (11) 0.082
  1. Abbreviations: ACE angiotensin converting enzyme; ARB angiotensin receptor blocker; BMI body mass index; CCB calcium channel blocker; GLS global longitudinal strain; GCS global circumferential strain; GRS global radial strain; IQR interquartile range; LVEF left ventricular ejection fraction; LVESVi left ventricular end-systolic volume index; LVEDVi left ventricular end-diastolic volume index; s.d standard deviation; LVMi left ventricular mass index; PTH parathyroid hormone