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Table 2 Univariate Associations with % Predicted VO2

From: Maldistribution of pulmonary blood flow in patients after the Fontan operation is associated with worse exercise capacity

Predictor

R or standardized β

Parameter Estimate ± SE

P value

Maldistribution of pulmonary blood flow (n = 147)

−0.17

−5.4 ± 2.6a

0.04

Mass-to-volume ratio (g/ml) (n = 140)

− 0.24

−19.38 ± 6.60b

0.004

Age at Fontan (year) (n = 139)

− 0.20

− 0.47 ± 0.19b

0.02

Old type Fontan (RA-PA or RA-RV conduit) (n = 146)

− 0.27

−9.2 ± 2.8a

0.001

CHF symptoms (n = 146)

− 0.21

−7.6 ± 2.9a

0.01

Atrial arrhythmia (n = 146)

− 0.29

−9.4 ± 2.6a

0.001

Fenestration (n = 139)

− 0.17

−1 ± 0.4a

0.04

Age at CMR (year) (n = 146)

− 0.36

− 0.55 ± 0.12b

0.001

Time since Fontan (year) (n = 139)

− 0.30

−0.67 ± 0.18b

0.001

Indexed end diastolic volume (ml/m2) (n = 145)

0.10

−0.03 ± 0.04b

0.90

Indexed end systolic volume (ml/m2) (n = 145)

−0.10

−0.07 ± 0.05b

0.16

Ejection fraction (%) (n = 145)

0.10

0.23 ± 0.14b

0.15

Indexed stroke volume (ml/m2) (n = 145)

0.01

0.01 ± 0.10b

0.94

Branch pulmonary artery symmetry index (n = 147)

0.04

2.52 ± 5.52b

0.64

Systemic left ventricle (n = 144)

0.01

−0.5 ± 3.0a

0.84

Heterotaxy (n = 147)

0.01

−3.3 ± 4.0a

0.41

  1. Abbreviations: PA pulmonary artery, RA right atrium, RV right ventricle
  2. aMean difference ± SE for presence vs. absence of maldistribution of pulmonary blood flow
  3. bSlope ± SE.SE = standard error