Table 1 Patient characteristics

Age, years (median, IQR)

50.1 (30.5–61.2)

50.1 (30.9–61.2)

0.01

Male, n (%)

30 (38)

60 (38)

1.00

Body mass index, kg/m2 (median, IQR)

29.0 (24.1–31.9)

29.1 (23.8–34.2)

0.10

Graft age, years (median, IQR)

2.74 (1.02–7.25)

N/A

N/A

Rejection, Grade > 3 ever, n (%)

19 (24.4)

N/A

N/A

Hypertension, n (%)

42 (54)

80 (51)

0.67

Diabetes mellitus, n (%)

19 (24)

27 (17)

0.20

Hyperlipidemia, n (%)

75 (96)

67 (43)

< 0.001

Current tobacco use, n (%)

1 (1)

16 (10)

0.003

Myocardial infarction^a, n (%)

3 (4)

25 (16)

0.004

Percutaneous intervention^a, n (%)

9 (12)

19 (12)

0.89

Coronary artery bypass graft^a, n (%)

0

8 (5)

0.06

Atrial fibrillation^a, n (%)

5 (6)

8 (5)

0.71

Cerebrovascular accident, n (%)

10 (13)

10 (6)

0.09

Chronic obstructive lung disease, n (%)

6 (8)

29 (19)

0.02

Serum creatinine, mg/dL (± SD)

1.12 (0.36)

0.87 (0.20)

< 0.001

 Angiotensin converting enzyme-inhibitor, n (%)

15 (19)

46 (29)

0.06

 Angiotensin receptor blocker, n (%)

17 (22)

21 (13)

0.14

 Beta-blocker, n (%)

10 (13)

65 (42)

< 0.001

 Calcium channel blocker, n (%)

18 (23)

19 (12)

0.04

 Aspirin, n (%)

72 (92)

59 (38)

< 0.001

 ADP/P2Y12 inhibitor, n (%)

7 (9)

13 (8)

0.87

 Statin, n (%)

72 (92)

53 (34)

< 0.001

 Glucocorticoid, n (%)

14 (18)

N/A

N/A

 Purine inhibitor, n (%)

72 (92)

N/A

N/A

 Calcineurin inhibitor, n (%)

66 (85)

N/A

N/A

 mTOR inhibitor, n (%)

18 (23)

N/A

N/A