Fig. 1

Example of the different late gadolinium enhancement (LGE) quantification methods in a patient with suspected myocarditis. a LGE-image with endocardium and epicardium is demarcated, b 2-SD (LGE: 28.9 g, 24.9% of total left ventricular (LV) mass); c 3-SD (19.4g, 16.8%); d 4-SD (12.2 g, 10.5%); e 5-SD (8.1g, 7.0%); f 6-SD (5.2 g, 4.5%); g 7-SD (3.3 g, 2.9%); h full width half maximum (FWHM) (14.7 g, 12.6%). Total LV mass was 116 g. The fibrosis is outlined in yellow. For 2 to 7-SD a region of interest (ROI) 1 is identified in the reference remote myocardium (yellow arrow/yellow contour). For FWHM, an automated ROI 2 is identified in the affected myocardium (pink arrow/pink contour). Of note, only the midventricular slice is represented, however, total LGE quantification includes mass and percentage of the entire left ventricle. SD = standard deviation