Table 2 Patient characteristics
Subjects [n] (%) | Total N = 132 (100) | IPH present N = 54 (40.6) | IPH absent N = 79 (59.4) | p-value |
|---|---|---|---|---|
Age [y] | 69.5 ± 8.6 | 69.4 ± 8.8 | 69.6 ± 8.5 | 0.918 |
Male sex [n] (%) | 69.2% | 45 (83.3) | 47 (59.5) | 0.004 |
Body mass index [kg/m2] | 26.7 ± 3.8 | 26.3 ± 3.0 | 27.0 ± 4.3 | 0.296 |
Currently smoking* [n] (%) | 21.1% | 8 (14.8) | 20 (25.6) | 0.015 |
Diabetes mellitus [n] (%) | 18.0% | 10 (18.5) | 14 (17.7) | 1.000 |
Hypertension [n] (%) | 65.4% | 43 (79.6) | 44 (55.7) | 0.005 |
Hypercholesterolemiaa [n] (%) | 51.9% | 32 (60.4) | 37 (47.4) | 0.158 |
Normalized wall index | 0.32 ± 0.23 | 0.43 ± 0.18 | 0.24 ± 0.23 | < 0.001 |
Statin use before most recent cerebrovascular event* [n] (%) | 58.6% | 35 (66) | 43 (54.4) | 0.209 |
Time between event and MRI [days] (range) | 28 (2–215) | 22.5 (2–215) | 34 (3–122) | 0.676 |
Degree of stenosis | ||||
 mild (0–29%) | 0.8% | 0 | 1 (1.3) | 0.056 |
 moderate (30–69%) | 66.2% | 30 (55.6) | 58 (73.4) | |
 severe (> 70%) | 31.6% | 22 (40.7) | 20 (25.3) | |
 occlusion | 1.5% | 2 (3.7) | 0 | |
Vessel wall K trans (/min) | 0.055 ± 0.015 | 0.051 ± 0.011 | 0.058 ± 0.017 | 0.001 |
Adventitia K trans (/min) | 0.057 ± 0.018 | 0.057 ± 0.017 | 0.057 ± 0.018 | 0.980 |