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Table 3 Association of carotid plaque features with ipsilateral ACI

From: Size of carotid artery intraplaque hemorrhage and acute ischemic stroke: a cardiovascular magnetic resonance Chinese atherosclerosis risk evaluation study

 

Presence of ACI

Univariate regression

Multivariate regression model 1d

Multivariate regression model 2 e

OR

95% CI

p

OR

95% CI

p

OR

95% CI

p

a Lumen area, mm2

1.058

0.898–1.247

0.501

0.975

0.819–1.161

0.776

   

a Wall area, mm2

1.269

1.081–1.489

0.004

1.257

1.047–1.510

0.014

   

a Total vessel area, mm2

1.194

1.014–1.406

0.034

1.109

0.924–1.331

0.268

   

a Mean wall thickness, mm2

1.293

1.103–1.515

0.002

1.315

1.103–1.568

0.002

   

b NWI, %

1.177

0.997–1.390

0.054

1.202

1.008–1.434

0.040

   

a Plaque volume, mm3

1.130

0.961–1.329

0.140

1.087

0.903–1.308

0.378

   

b Luminal stenosis, %

1.098

1.044–1.155

< 0.001

1.096

1.039–1.155

0.001

   

Presence of calcification

1.050

0.754–1.463

0.772

1.094

0.757–1.582

0.632

1.024

0.680–1.541

0.910

Presence of FCR

1.140

0.637–2.042

0.659

1.183

0.646–2.167

0.586

1.095

0.578–2.074

0.780

Presence of LRNC

0.901

0.611–6.328

0.597

0.780

0.516–1.180

0.240

0.663

0.417–1.054

0.083

Presence of IPH

1.489

0.979–2.266

0.063

1.515

0.963–2.384

0.072

1.485

0.907–2.432

0.116

c Volume of calcification, mm3

0.971

0.763–1.234

0.808

1.023

0.794–1.318

0.859

0.953

0.702–1.294

0.759

c % calcification volume, %

0.605

0.314–1.166

0.133

0.731

0.372–1.436

0.363

   

c Volume of LRNC, mm3

1.297

1.084–1.553

0.005

1.312

1.082–1.591

0.006

1.398

1.045–1.870

0.024

c % LRNC volume, %

1.199

1.032–1.393

0.018

1.190

1.014–1.398

0.034

   

c Volume of IPH, mm3

2.514

1.363–4.637

0.003

2.907

1.341–6.301

0.007

2.813

1.212–6.528

0.016

c % IPH volume, %

2.202

1.317–3.680

0.003

2.374

1.324–4.257

0.004

   
  1. NWI normalized wall index, FCR fibrous cap rupture, LRNC lipid-rich necrotic core, IPH intraplaque hemorrhage. a The increment for plaque burden was 1 SD. b The increment for NWI and luminal stenosis was 10% NWI and stenosis. c Only for patients with the corresponding plaque compositional feature with increment of 1 SD for composition size and 10% for percent of composition volume. d Model 1: adjustment for age, gender, BMI, hypertension, hyperlipidemia, CHD, diabetes, and smoke. e Model 2: adjustment for the former clinical factors and plaque volume