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Table 3 Association of carotid plaque features with ipsilateral ACI

From: Size of carotid artery intraplaque hemorrhage and acute ischemic stroke: a cardiovascular magnetic resonance Chinese atherosclerosis risk evaluation study

  Presence of ACI
Univariate regression Multivariate regression model 1d Multivariate regression model 2 e
OR 95% CI p OR 95% CI p OR 95% CI p
a Lumen area, mm2 1.058 0.898–1.247 0.501 0.975 0.819–1.161 0.776    
a Wall area, mm2 1.269 1.081–1.489 0.004 1.257 1.047–1.510 0.014    
a Total vessel area, mm2 1.194 1.014–1.406 0.034 1.109 0.924–1.331 0.268    
a Mean wall thickness, mm2 1.293 1.103–1.515 0.002 1.315 1.103–1.568 0.002    
b NWI, % 1.177 0.997–1.390 0.054 1.202 1.008–1.434 0.040    
a Plaque volume, mm3 1.130 0.961–1.329 0.140 1.087 0.903–1.308 0.378    
b Luminal stenosis, % 1.098 1.044–1.155 < 0.001 1.096 1.039–1.155 0.001    
Presence of calcification 1.050 0.754–1.463 0.772 1.094 0.757–1.582 0.632 1.024 0.680–1.541 0.910
Presence of FCR 1.140 0.637–2.042 0.659 1.183 0.646–2.167 0.586 1.095 0.578–2.074 0.780
Presence of LRNC 0.901 0.611–6.328 0.597 0.780 0.516–1.180 0.240 0.663 0.417–1.054 0.083
Presence of IPH 1.489 0.979–2.266 0.063 1.515 0.963–2.384 0.072 1.485 0.907–2.432 0.116
c Volume of calcification, mm3 0.971 0.763–1.234 0.808 1.023 0.794–1.318 0.859 0.953 0.702–1.294 0.759
c % calcification volume, % 0.605 0.314–1.166 0.133 0.731 0.372–1.436 0.363    
c Volume of LRNC, mm3 1.297 1.084–1.553 0.005 1.312 1.082–1.591 0.006 1.398 1.045–1.870 0.024
c % LRNC volume, % 1.199 1.032–1.393 0.018 1.190 1.014–1.398 0.034    
c Volume of IPH, mm3 2.514 1.363–4.637 0.003 2.907 1.341–6.301 0.007 2.813 1.212–6.528 0.016
c % IPH volume, % 2.202 1.317–3.680 0.003 2.374 1.324–4.257 0.004    
  1. NWI normalized wall index, FCR fibrous cap rupture, LRNC lipid-rich necrotic core, IPH intraplaque hemorrhage. a The increment for plaque burden was 1 SD. b The increment for NWI and luminal stenosis was 10% NWI and stenosis. c Only for patients with the corresponding plaque compositional feature with increment of 1 SD for composition size and 10% for percent of composition volume. d Model 1: adjustment for age, gender, BMI, hypertension, hyperlipidemia, CHD, diabetes, and smoke. e Model 2: adjustment for the former clinical factors and plaque volume