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Table 2 Ten-fold cross-validation results from penalized logistic regression models using the first 50 PCA modes (PCA50) and from the reference baseline mass/volumes (MassVol) measurement models

From: Right ventricular shape and function: cardiovascular magnetic resonance reference morphology and biventricular risk factor morphometrics in UK Biobank

Factor

Model

AUC

Sensitivity

Specificity

Precision

F1-score

npv

Cutoff

Cholesterol

MassVol

0.587

0.704

0.451

0.346

0.464

0.787

0.495

PCA50*

0.751

0.792

0.579

0.437

0.564

0.871

0.485

Smoking

MassVol

0.594

0.856

0.287

0.334

0.480

0.826

0.490

PCA50*

0.699

0.525

0.795

0.517

0.521

0.800

0.511

Diabetes

MassVol

0.652

0.740

0.554

0.342

0.468

0.872

0.494

PCA50*

0.817

0.704

0.781

0.502

0.586

0.894

0.504

Previous MI

MassVol

0.733

0.699

0.663

0.235

0.351

0.937

0.490

PCA50*

0.853

0.677

0.911

0.529

0.594

0.950

0.518

Angina

MassVol

0.671

0.700

0.637

0.196

0.307

0.944

0.497

PCA50*

0.773

0.663

0.763

0.262

0.376

0.947

0.493

Obesity

MassVol

0.682

0.675

0.598

0.638

0.656

0.637

0.494

PCA50*

0.839

0.760

0.763

0.771

0.766

0.752

0.500

Hypertension

MassVol

0.651

0.693

0.543

0.718

0.705

0.514

0.495

PCA50*

0.770

0.752

0.663

0.789

0.770

0.615

0.494

  1. Statistical tests were performed between MassVol and PCA50. Significant differences (p < 0.005) are represented with an asterisk
  2. PCA principal component analysis, MI myocardial infarction