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Table 2 Relationship between right ventricular fibrotic load and right ventricular function among cases with repaired tetralogy of Fallot

From: Genetic variants of HIF1α are associated with right ventricular fibrotic load in repaired tetralogy of Fallot patients: a cardiovascular magnetic resonance study

 

Indexed fibrotic volume

Fibrotic score

Linear Model

βa

SE

p-value

βa

SE

p-value

 RVEF

−1.58

0.78

0.04

−0.89

0.39

0.03

 Log RVEDVI

0.03

0.02

0.25

0.02

0.01

0.18

Dichotomized modelb

ORa

95% CI

p-value

ORa

95% CI

p-value

 RVEF

1.72

0.99, 2.96

0.052

1.37

1.06, 1.78

0.02

 RVEDVI

1.21

0.72, 2.03

0.46

1.06

0.81, 1.38

0.68

  1. CI confidence interval, RVEDVI indexed right ventricular end-diastolic volume, RVEF right ventricular ejection fraction, OR odds ratio, SE standard error
  2. a Adjusted for time between the first and second CMR, time between repair and first CMR, body mass index, pulmonary regurgitant fraction, and obstruction
  3. b RVEF< 50%, RVEDVI> 108 cc/m2 considered abnormal