Table 3 Univariate Cox Regression Models for Time to 1-Year Composite Outcome in the Prospective Cohort, Stratified by Heart Failure
From: Quantification of lung water in heart failure using cardiovascular magnetic resonance imaging
Univariate Predictors | Patients with or at risk for HF (N = 203, 34 events) | Only Patients with HF (N = 121, 28 events) | ||||
|---|---|---|---|---|---|---|
HR | 95% CI | p-value | HR | 95% CI | p-value | |
Age at CMR, 10 year | 1.9 | (1.3, 2.8) | < 0.001 | 1.8 | (1.2,2.6) | 0.004 |
Female gender | 1.4 | (0.7, 2.8) | 0.31 | 1.8 | (0.8, 3.8) | 0.13 |
BMI, 1 kg/m2 | 1.0 | (0.9, 1.1) | 0.75 | 0.9 | (0.9. 1.0) | 0.06 |
Current smoker | 1.0 | (0.4, 2.9) | 0.96 | 0.6 | (0.2. 2.7) | 0.54 |
Diabetes | 1.3 | (0.7, 2.6) | 0.42 | 1.2 | (0.6. 2.6) | 0.62 |
Hypertension | 0.7 | (0.3, 1.5) | 0.4 | 0.9 | (0.4. 1.9) | 0.77 |
CAD/MI | 1.2 | (0.6, 2.4) | 0.58 | 0.9 | (0.4. 1.8) | 0.69 |
Atrial Fibrillation | 1.3 | (0.6, 2.6) | 0.48 | 0.9 | (0.4. 1.9) | 0.73 |
COPD | 1.7 | (0.8, 3.8) | 0.18 | 1.3 | (0.5, 3.0) | 0.58 |
History of heart failure | 3.5 | (1.4, 8.4) | 0.006 | na | na | na |
NYHA class III or IV | 4.1 | (2.0, 8.2) | < 0.001 | 2.9 | (1.4, 6.2) | 0.005 |
Beta blocker at baseline | 3.1 | (1.2, 8.0) | 0.02 | 1.4 | (0.4, 4.5) | 0.62 |
ACEi or ARB at baseline | 1.2 | (0.5, 3.1) | 0.71 | 0.9 | (0.3, 2.8) | 0.94 |
Loop diuretic at baseline | 2.4 | (1.2, 4.8) | 0.02 | 1.4 | (0.6, 3.3) | 0.42 |
Systolic BP, 10 mmHg | 1.0 | (0.8, 1.1) | 0.56 | 1.1 | (0.9. 1.3) | 0.56 |
BNP, 100 pg/ml | 1.2 | (1.1, 1.3) | < 0.001 | 1.2 | (1.1, 1.3) | < 0.001 |
Creatinine, 10 umol/L | 1 | (1.0, 1.2) | 0.033 | 1.0 | (0.9, 1.1) | 0.53 |
LVEF, 10% | 0.9 | (0.7, 1.1) | 0.35 | 1.1 | (0.9, 1.5) | 0.43 |
Lung water density > 20.8% | 2.6 | (1.3, 5.6) | 0.005 | 2.6 | (1.3, 5.6) | 0.01 |