| Healthy Control Group (n = 30) | Myocarditis Group (n = 50) | p Value |
---|---|---|---|
Age (y) | 36.9 ± 13.5 | 38 ± 16.3 | 0.764 |
Male (%) | 23 (77) | 37 (74) | 0.505 |
BMI (kg/m2) | 25.3 ± 4.1 | 25.4 ± 5.2 | 0.937 |
CMR results | |||
 Symptom onset to CMR (d) | – | 2.9 ± 1.8 | – |
 Heart rate (bpm) | 68.1 ± 12.4 | 74.1 ± 15.2 | 0.170 |
 LVEF (%) | 61.6 ± 4.6 | 55.3 ± 9.4 | 0.004 |
 LVEDV/BSA (ml/m2) | 74.3 ± 9.4 | 78.1 ± 17.1 | 0.552 |
 IVST (mm) | 9.5 ± 1.6 | 9.8 ± 1.7 | .311 |
Blood values | |||
 Max. Trop I (ng/ml) | – | 18.9 ± 78.2 | – |
 Leucocytes (103/μmL) | 6.5 ± 1.7 | 10.4 ± 4.7 | 0.001 |
 C-reactive protein (mg/L) | 1.0 ± .8 | 70.7 ± 99 | <0.001 |
 CK-MB mass | – | 21.4 ± 36.6 | – |
 Creatine kinase (U/L) | – | 363.5 ± 489.8 | – |
 Haematocrit (%) | 41.7 ± 3.9 | 40.5 ± 5.6 | 0.304 |
Number of patients with myocarditis specific parameters (%) | |||
 Fulfilling the LLC (%) | 0 (0) | 36 (72) | <0.001 |
 T2 ratio/visible edema (%) | 2 (7) | 33 (66) | <0.001 |
 EGEr/aME (%) | 6 (20) | 24 (59) | 0.001 |
 LGE (%) | 0 (0) | 39 (78) | <0.001 |
Myocarditis specific parameters | |||
 T2 SI myocardium | 763.5 ± 268.9 | 893.4 ± 262.7 | 0.004 |
 T2 SI skeletal muscle | 472.5 ± 157.3 | 465 ± 132.8 | 0.826 |
 T2 ratio | 1.6 ± 0.3 | 1.9 ± 0.4 | <0.001 |
 EGEr | 2.3 ± 1.9 | 3.1 ± 1.8 | 0.063 |
 aMe (%) | 37.5 ± 18.3 | 54.4 ± 31.6 | 0.007 |
 LGE in % | 0 | 12,1 ± 11.8 | – |