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Table 2 Subgroup analysis of repaired CoA subject with and without VAH + ipCoW

From: Repaired coarctation of the aorta, persistent arterial hypertension and the selfish brain

 Repaired coarctation patientsp-value
No VAH + ipCoW
(n = 81)
VAH + ipCoW
(n = 46)
Demographic data
 Age (years)33 ± 1435 ± 12= 0.32
 Male gender n [%]46 [57]31 [67]= 0.26
 BMI (kg/m2)25 ± 526 ± 5= 0.13
Blood pressure data
 Office SBP (mmHg)134 ± 18145 ± 20<  0.003
 Office DBP (mmHg)75 ± 1077 ± 11= 0.17
 Uncontrolled HTNa n [%]5 [6]8 [18]= 0.064
 On anti-HTN Rx n [%]27 [33]25 [54]= 0.025
 ACEi /ARB n [%]41 [50]29 [64]= 0.31
 CCB n [%]16 [20]12 [26]= 0.74
 Beta-blocker n [%]36 [44]19 [42]= 0.99
Other congenital heart defects
 Bicuspid aortic valve n [%]66 [81]28 [61]= 0.14
 Ventriculoseptal defect13 [16]4 [9]= 0.30
Coarctation repair datab
 Age at repair (years)5 (0–39)7 (0–59)= 0.41
 End to End repair n [%]29 [47]19 [51]= 0.68
 Subclavian flap n [%]14 [23]6 [16]= 0.61
 Patch repair n [%]8 [13]7 [19]= 0.56
 Angioplastyc n [%]11 [18]5 [14]= 0.78
 Recoarctation n [%]43 [52]19 [41]= 0.35
  1. ACEi angiotensin converting enzyme inhibitor, ARB angiotensin receptor blocker, CCB calcium channel blocker, HTN hypertension
  2. a Uncontrolled hypertension definition: office BP > 140/90 mmHg despite at least 2 anti-hypertensive medications
  3. b Repair data = median (range), total n = 99, no VAH + iCoW n = 62, VAH + iCoW n = 37
  4. c Angioplasty is pooled balloon and stent angioplasty subgroups